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在三元溶液低温相变过程中细胞反应的数值模拟(英文) 被引量：1

Numerical Simulation of Cell Response in Freezing of Ternary Solution
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摘要 应用多组分相变系统的连续体模型 ,对三元溶液 (NaCl H2 O CPA)低温相变过程中的细胞反应进行数值模拟 .为了检验数值分析的结果 ,在特定条件下 ,提出一种解决多组分系统相变问题的近似分析方法 ,并在相同条件下 ,将此结果与数值分析的结果进行比较 。 Using the continuum model for multi-component phas e change system, the freezing process of ternary cell solution (H 2O-NaCl-CPA) was simulated numerically. In order to verify the results of numerical simulat ion, with some specific assumptions, an approximate analytical method was deve loped. Results of numerical simulation and analytical method were compared unde r the same conditions.Their coincidence shows the numerical simulation to be ri ght basically.
作者 罗大为 高大勇 程曙霞 何立群
机构地区 中国科学技术大学热科学与能源工程系
出处 《中国科学技术大学学报》 CAS CSCD 北大核心 2003年第1期84-91,共8页 JUSTC
基金 SupportedbyGrantsfromtheHundredsScholarshipofCAS(2 0 0 1-2 0 0 3 )theNSFC(No .5 99760 41)
关键词 相变传热 细胞模型 成核机制 低温损伤 phase change heat conduction cell model nucleation mechanism cryoinjury
分类号 Q274 [生物学—细胞生物学] Q273 [生物学—细胞生物学]
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参考文献13

  • 1[1]Mazur P. Freezing of living cells: Mechanism and implications [J]. Am. J. Physiol. Cell Physiol. 1984, 247 (16): C125-142.
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同被引文献7

  • 1Cooke R, Kuntz I D. The properties of water in biological systems [A]. Annu. Rev. Biophys.Bioeng. 3 [C]. Ed. Mullins L J. California:Annual Reviews Inc. , 1974. 95-126.
  • 2Cooke R, Wien R. The state of water in muscle tissue as determined by proton nuclear magnetic resonance [J]. Biophys. J, 1971, 11:1002-17.
  • 3Ramachandra V D, Debopam R and John C B.Measurement of water transport during freezing in cell suspensions using differential scanning calorimetry [J]. Cryobiology, 1998, 36: 124-155.
  • 4Luo Da-wei, Han Xu, He Li-qun, et al. A modified differential scanning calorimetry for determination of cell volumetric change during the freezing process [ J ]. Cryo-Letters, 2002,23 : 229-236.
  • 5Farrant J and Woolgar A E. Human red cells under hypertonic conditions; a model system for investigating freezing damage. I. Sodium chloride [J]. Cryobiology, 1972, 9: 9-15.
  • 6Wolfe J, Bryant G and Koster K L. What is ‘unfreezable water', how unfreezable is it and how much is there? [J]. Cryo-Letters, 2002,23 : 157-166.
  • 7Franks F. Unfrozen water: yes; unfreezable water: hardy; bound water: certainly not [ J ].Cryo-Letters, 1986, 7 : 207.

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中国科学技术大学学报
2003年 第1期

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