摘要
异基因造血干细胞移植是治疗血液系统疾病、自身免疫性疾病和某些实体瘤的有效手段。移植后供体干细胞是否植活形成嵌合体及其动态演变过程不仅影响着疾病的转归,还对临床治疗具有重要的指导意义。用于判断移植后造血干细胞植活直接依据主要依赖于体内各种遗传标记。目前利用遗传标记对受者进行嵌合状态分析的方法有很多,可归为生化方法、细胞遗传学方法和分子遗传学方法三类。本文就目前常用的嵌合体分析方法作一综述。
出处
《国外医学（内科学分册）》
2003年第3期118-122,共5页
Foreign Medical Sciences(Section of Internal Medicine)
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