三叉神经痛伽玛刀的双靶点治疗

Bi-target Treatment of Trigeminal Neuralgia by Gamma Knife.

目的 :探讨利用双靶点提高伽玛刀治疗原发性三叉神经痛有效率和降低复发率的可能性。方法 :选择 32例原发性三叉神经痛的患者 ,双靶点位于三叉神经近脑桥处和近半月神经节 ,用 4mm准直器 ,中心计量 80～ 90Gy ,桥脑临界计量 <2 0Gy。 结果 :随访 0 .5～ 5年 ,有效率为 10 0 % ,有两例复发 .除 7例病人面部麻木外 ,未见其他并发症。结论 :双靶点治疗比单靶点治疗近期观察可提高有效率降低复发率。长期疗效、复发率尚待进一步随访观察和研究。

Objective:To investigate the improving effectiveness and possibilities of decreasing the recurrence of trigeminal neuralgia by utilizing bi-target treatment of gamma knife.Methods:Excerpt 32 cases patients who suffered from primary trigeminal neuralgia,bi-target located at trigeminal point nearby pons and gasserianganglion, using 4mm collimator,center measure 80～90Gy, pons critical dosage <20Gy.Results:Following up half a year to 5 years, effectiveness is 100%. 2 cases among them recurred. Except 7 cases patients who suffered facial numbing, no other complication was found.Conclusions:Comparing to single-target treatment of gamma knife, bi-target treatment gamma knife is better in improving effectiveness and decreasing recurrence when it was observed in the short term. But as to in long term, further observation and research is needed.