碘干预与贵州病区儿童几项生化指标比较分析

A Comparison Study on Tg,FT_3,FT_4 and TSH after Iodine Intervention in Schoolchildren

目的 了解碘干预后 ,不同碘缺乏病区儿童血清学指标的变化。方法 选择历史重、轻病区县各 1个 ,对 7～ 14岁儿童尿碘及血清Tg ,FT3 ,FT4 ,TSH调查。结果 碘缺乏病病区儿童尿碘水平已达到国家IDD控制标准 ,TSH ,FT3 FT4 几项血清生化指标也在药盒提供的正常范围。Tg则很低。结论 应开展对Tg下线值的研究 。

Objective To search the changing in different areas with iodine deficiency on Tg, FT_3, FT_4 and TSH in schoolchildren after iodine intervention. Methods Both severe and slightly area with Iodine Deficiency Disorders (IDD) were selected, studying on urinary iodine (UI),Tg, FT_3, FT_4 and TSH in schoolchildren aged 7～14. Results IDD has achieved the national standard of elimination IDD with UI 386.4μg/L and 473.9μg/L in both severe and slightly IDD areas after iodine intervention 20 years. FT_3,FT_4 and TSH were as normal. However, the Tg was lower than normal indicator. Conclusions The normal value of Tg should be studied which would be significant for both prevention and surveillance of IDD.