新生儿高胆红素血症不同换血速度与胆红素下降速度的关系

Relationship Between Blood-exchange Speed and Reduction of Blood Bilirubin Values in Neonates with Hyperbilirubinemia

目的了解换血速度与胆红素下降速度的关系。方法同步经外周动脉抽血、静脉输血 ,将换血时间 <2 .5h者归为短时组 ,≥ 2 .5h者归为长时组。比较两组患儿换血后胆红素水平及胆红素下降的速度、百分比及下降值。结果两组患儿换血前、后的胆红素水平及胆红素的下降值、百分比 ,差异无显著性意义 (P >0 .0 5 ) ,但在换血量一定的情况下 ,换血时间短 ,换血速度越快 ,胆红素下降速度越快 (P <0 .0 1)。结论换血量一定的情况下 ,换血时间的长短与胆红素下降的最终水平差异无统计学意义。但是换血速度快 ,胆红素下降速度快 ;换血速度慢 。

Objective To observe the relationship between blood exchange speed and reduction of blood bilirubin values . Methods The blood exchange was carried out through peripheral artery and vein. In terms of the blood exchange time, the neonates with hyperbilirubinemia were divided into two groups: short time group (<2.5 h) and long time group (≥2.5 h). The levels of blood bilirubin after blood exchange, decreased values, reduction velocity and percentage were compared between two groups. Results There was no significant difference in the levels of blood bilirubin after blood exchanges and decreased values after blood exchange between the two groups ( P > 0.05 ). Under the certain blood exchange quantity, the shorter the blood exchange, the more blood quantity was extracted out and the faster the reduction of bilirubin. Conclusion There was no relationship between the blood exchange time and the final levels of blood bilirubin in the two groups. But under the certain blood exchange quantity, the blood exchange speed was related with the reduction of blood bilirubin.