摘要
通过间歇吸附动力学实验 ,采用孔扩散模型研究了牛血清白蛋白和γ 球蛋白在阴离子交换剂中的扩散行为 ,考察了蛋白质初浓度和平均吸附密度对孔扩散系数的影响 .结果表明 ,随蛋白质初浓度和平均吸附密度增大 ,孔扩散系数均呈指数下降 。
The ion-exchange adsorption kinetics of bovine serum albu mi n (BSA) and γ-globulin into an anion exchanger,DEAE-Spherodex M, has been studied by batch adsorption experiments.The pore diffusion model was used to p redict pore diffusivity.The effect of initial protein concentration and average adsorption density on pore diffusivity was investigated.The results showed tha t pore diffusivity decreased exponentially with increasing initial protein conce ntration and average adsorption density. Moreover, the larger the dimension of the protein, the greater the decline of pore diffusivity was observed.
出处
《化工学报》
EI
CAS
CSCD
北大核心
2003年第2期215-220,共6页
CIESC Journal
基金
国家杰出青年科学基金资助项目 (No.2 0 0 2 5 617)~~
