α,β-不饱和羰基锆化合物的合成及其在高选择合成中的应用

A Stereoselective Synthetic Route to (E)- α,β-Unsaturated Thioesters

由端炔和Cp2Zr(H)Cl(Cp=η5-C5H5)及CO反应,得到α,β-不饱和羰基锆化合物,进而与芳基硫 氯反应,合成了α,β-不饱和羧酸硫酯,产率中等至良好.

Terminal alkynes 1 react with Cp2Zr(H)Cl (Cp = η 5-C5H5) and CO to give acylzirconocene chloride derivatives 2, which are trapped with arylsulfenyl chloride to afford (E)- α,β-unsaturated thioesters 3.