部队干休所老年人轻度认知功能损害调查

Study of the prevalence of mild cognitive impairment in elderly veterans

目的 了解老年人轻度认知功能损害 (MCI)的现状 ,为研究Alzheimer病 (AD)提供依据。 方法 采用中文版简易智能状态检查 (MMSE)、总体衰退量表、日常生活能力、哈金斯基缺血指数及汉密尔顿抑郁量表等量表为筛查工具 ,对石家庄市 2 6个部队休干所的 2 6 74名≥ 6 0岁的离退休干部进行MCI患病率调查。 结果 老年人MCI的患病率为 8 0 8% ,其中男性标化患病率为6 87% ,女性标化患病率为 10 38% ,女性高于男性 (P <0 0 1) ;老年人MCI的患病率随年龄增长有升高的趋势 (P <0 0 1) ;随着文化程度的提高 ,MCI患病率有降低的趋势 (P <0 0 5 )。 结论 部队干休所老年人MCI的患病率低于欧美国家。应加强对老年MCI患者这一痴呆高危人群进行监测 ,早期进行干预治疗 ,从而延缓或阻止病情进展为AD。

Objective To explore the prevalence of mild cognitive impairment (MCI) among elderly veterans. Methods 2 674 veterans ( aged 60 years and over) from 26 military sanatorium in Shijiazhuang city were studied. The Mini-Mental State Examination, Global Deterioration Scale, Activity of Daily Living, Hachinski Ischemic Scale and Hamilton Depression Scale were served as screening tools. Results The prevalence of total MCI was 8 08% in elderly people. The standardized prevalence of MCI was 6 87% in male and 10 38% in female (P<0 01). The prevalence of MCI tended to increased with aging (P<0 01) and decreased with the elevated degree of education (P<0 05). Conclusions The prevalence of MCI in elderly veterans in China is lower than that in European and American countries. We should be intensive to monitor the MCI people who are in a high risk for Alzheimer disease. The intervention treatment for MCI should be turn into the second prevention of the Alzheimer disease.