血小板衍化生长因子对离体牙周膜细胞增殖的影响

The Effects of Platelet-derived Growth Factor-β on the Proliferation of Human Periodontal Ligament Cells in Vitro

目的 :探讨血小板衍化生长因子 β (Platelet derivedgrowthfactor β ,PDGF β)对离体人牙周膜细胞(periodontalligamentcells,PDLCs)增殖的影响。方法 :体外培养人PDLCs,与不同浓度的PDGF β作用 ,用噻唑蓝 (MTT)比色法进行观察。结果 :PDGF β作用后PDLCs的增殖较对照组有明显的升高 ,而且具有浓度效应。结论 :PDGF

Objective:To evaluate the effects of Platelet derived growth factor β (PDGF β) on the proliferation of periodontal ligament cells (PDLCs). Methods: Using cell culture technique, enzyme kinetics methods. Results: The proliferation of PDLCs increased markedly under the effects of PDGF β,and the increase related to the concentration of PDGF β .Conclusion: PDGF β could promote the proliferation of PDLCs.