老年糖尿病足的危险因素分析

Risk Factors Causing Diabetic Foot in Aged Patients with Type 2 Diabetes Mellitus

目的 :分析老年 2型糖尿病并发糖尿病足的危险因素。方法 :检测老年 2型糖尿病并发糖尿病足患者 2 3例及未并发糖尿病足患者 4 8例的糖化血红蛋白 (GHbA1c)、血胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白胆固醇(HDL C)、收缩压 (SBP)、舒张压 (DBP)、踝动脉 -肱动脉血压比值 (ABI)等指标 ,同时检查糖尿病足患者是否合并其它糖尿病慢性并发症。结果 :糖尿病足组与非糖尿病足组比较 ,GHbA1c、TG、SBP、DBP增高 ,HDL C、ABI降低 ,两组比较有显著差异 (P <0 .0 5 )。糖尿病足组患者常伴有周围神经病变、视网膜病变、高血压等慢性并发症 ,尤其以周围神经病变多见。结论 :老年糖尿病患者并发糖尿病足与高血糖、高甘油三酯血症、高血压显著相关 ,周围神经病变、周围血管病变在糖尿病足发病中具有重要作用。严格控制血糖、血脂。

Objective:To evaluate risk factors causing diabetic foot (DF) in aged patients with type 2 diabetic mellitus.Methods:Concentrations of GHbA 1c ?TC? TG,and HDL C in the serum were detected and SBP,DBP, and ABI were measured in 71 diabetes mellitus cases with or without DF. Meanwhile, all cases were examined for any other chronic complications.Results:There was a significant increase( P <0.05) in the concentrations of GHbA1c,TG,SBP, and DBP between the group of DF and the group of non DF,and a significant decrease( P <0.05) in HDL C and ABI in the group of DF.The patients with DF usually complained of chronic complications such as peripheral neuropathy,retinopathy, hypertension,etc.Conclusion:There would be a significant relevant between DF and hyperglucose?hypertriglyceridemia and hypertension in the aged DM.Peripheral neuropathy, peripheral vessel disease play a main role in the etiology of DF.It is important to prevent from DF that controlling exactly blood glucose,plasma lipids,and blood pressure.