塞克硝唑阴道泡腾片的制剂工艺和质量研究

Study of Secnidazole Vaginal Effervescent Tablets and Its Standard

目的 :对塞克硝唑阴道泡腾片的制剂工艺和质量进行研究。方法 :采用紫外分光光度法测定主药塞克硝唑的含量。结果 :线性范围为 5 1 5～ 36 0 5μg/ml,相关系数为 0 9999,线性关系良好 ,平均回收率为 1 0 0 3 % ,RSD为 0 36 % (n =9)。结论 :本制剂设计合理 ,稳定性好 。

AIM:Preparation of secnidazole vaginal effervescent tablets and study of its standard Methods: Quantitative determination of Secnidazole by UV spectroscopy Results:In the concentration range of 5 15～36.05 μg/ml, the average recovery is 100 3%, and the RSD is 0 36%( n=9 ) Conclusions:The vaginal effervescent tablets are stable and useful for the clinic \;