腹水超滤浓缩回输治疗肝硬变顽固性腹水

Ultrafiltration of ascites and peritoneal reinfusion of ascites for the treatment of refractory cirrhotic ascites

目的观察腹水超滤浓缩腹腔回输治疗肝硬变顽固性腹水的疗效与安全性。方法采用WLFHY 50 0型伟力电脑腹水超滤浓缩回输系统 ,对 2 3例肝硬变顽固性腹水患者行 2 9例次治疗 ,观察患者体重、腹围、2 4小时尿量及尿钠排出量、血肌酐、尿素氮、电解质、白蛋白等变化 ,随访 3个月以上 ,对疗效进行判定。结果经治疗后 ,患者 2 4小时尿量及尿钠增加 ,血清白蛋白水平增加 ;尿素氮、肌酐、电解质水平无显著性变化 ,总有效率达 6 5.5% ,无严重并发症。结论腹水超滤浓缩腹腔回输治疗肝硬变顽固性腹水 ,方法简便易行 ,且安全有效。

Objective To observe the efficacy and safety of ultrafiltration and peritoneal reinfusion of ascites to treat refractory cirrhotic ascites. Methods 23 cirrhotic patients with refractory ascites were treated for 29 times with WLFHY 500 ultrafiltration and peritoneal reinfusin system.The body weight, abdomen circumference, urine volume and urinary natrium output in 24 hours, serum levels of blood urea nitrogen, creatinine, albumin, kalium, natrium and chlorine ions were observed and compared before and after treatment.All patients were followed up for more than 3 months to determine the efficacy. Results After the treatment with ultrafiltration and peritoneal reinfusion of ascites, urine volume and urinary natrium output in 24 hours were elevated and serum albumin was elevated(P<0.01). The serum levels of blood urea nitrogen, creatinine, kalium, natrium and chlorine ions were not significantly changed(P>0.05). The overall efficacy rate was 65.5%. No severe complication occurred. Conclusion Ultrafiltration of ascites and peritoneal reinfusion of ascites is safe and simple to operate with effect.