氟喹诺酮类抗菌药物与过渡金属离子Cr^(3+),Mn^(2+) 和Fe^(3+)形成配合物配位位置的研究

THE COMPLEX SITES OF METAL IONS Cr^(3+), Mn^(2+) AND Fe^(3+) WITHFLUOROQUINOLONE ANTIMICROBIALS STUDIED BY NMR METHODS

通过 1D1 HNMR ,1 3CNMR和1 H自旋 晶格弛豫时间T1 对氟喹诺酮类抗菌药物与过渡金属离子Cr3+,Mn2 +和Fe3+形成配合物的位置进行了研究 ,合成了固体配合物 ,对其进行了元素分析 .实验结果表明过渡金属离子Cr3+,Mn2 +和Fe3+与氟喹诺酮类抗菌药物形成 1∶2的配合物 。

By measuring 1H and 13 C NMR signals and 1H spin lattice relaxation time T 1, we have studied the complexes formed between fluoroquinolone antimicrobials and metal ions Cr 3+ , Mn 2+ and Fe 3+ . The complex sites of the metal ions with fluoroquinolone antimicrobials were measured.