开放式的高分辨率超声成像系统(英文)

Open System for High Resolution Ultrasound Imaging

在医学和生物学研究当中,对活体组织进行无创性成像具有重要意义。高分辨率超声成像技术,可以对细微组织实现高空间分辨率的成像,已被广泛应用于皮肤、眼睛、心血管和小动物成像等生物医学领域。目前领域内的相关研究需要不同的成像系统参数,例如要求不同的探头性能、数据采集策略、信号处理以及图像重建、显示和保存方法。因此需要一种灵活和开放的超声成像系统,能让用户根据各种研究需求实现个性化设置并能全面获取原始实验数据。文章提出了一种实时的、便携式设计的开放式超声成像系统,可支持定制的高分辨率超声成像研究。系统基于高速现场可编程逻辑门阵列(FPGA)实现灵活多样的超声成像。用户可以轻松地根据个性化应用需求来调整系统结构。测试结果表明,本系统能实现B超成像、编码激励成像、多普勒成像、血管内成像、多模态组合成像等,为高分辨率生物医学应用研究提供了非常灵活的成像工具。

Noninvasive visualization of living tissues is in great demand in the field of medical and biological studies.High resolution ultrasound imaging has made it possible to image small structures with fine spatial resolution and been widely used in the biomedical field including the dermatology, ophthalmology, intravascular imaging, and small animal imaging. The individual study is unique in nature and requires different utilization of the imaging system, such as different transducer characteristics, data acquisition strategies, signal processing methods, and image reconstruction, display and storage. Therefore, there is a demand for a flexible and open imaging system to allow users to customize the system for various studies and have full access to experimental data. In this paper, a real-time compact and open system is developed for customized high resolution ultrasound imaging studies. The system was based on high-speed field programmable gate array(FPGA) embedded in compact printed circuit board(PCB) to achieve flexible ultrasound imaging. The system structure could easily be modified by the users for customized applications. Testing results show that the system can offer a very flexible setting with B-mode imaging, modulated excitation imaging, Doppler imaging, intravascular imaging, and multi-modality imaging for high resolution biomedical applications.