失代偿期肝硬化患者钠代谢紊乱及其预后

Sodium metabolic disorder in decompensated cirrhosis patients and prognosis

目的 探讨肝硬化失代偿期患者钠代谢的变化及其预后。方法 对 138例失代偿期肝硬化患者进行钠检测及肝功能child - pugh分级。 结果 4 6 .4 %的患者发生低钠血症 ,且随肝功能分级的增高而明显 ,合并腹水时低钠血症的发生率 5 8.6 % ,低钠血症时肝硬化的并发症及病死率明显增高。结论 肝硬化患者易并发低钠血症 ,其发生与腹水的产生及肝功能状况有关 ,易引起严重并发症 。

Objectives To explore the alteration of Na metabolism and prognosis of patients with decompensated cirrhosis.Methods Serum sodium concentration were chemically determined and hepatic function levels were classified with child-pugh method in 138 decompensated cirrhosis patients.Results Hyponatremia incidence in patients with decompenasted cirrhosis was 46.4%,and would slightly go up with the increase of hepatic function impairment and with ascites occurrence(58.6%).Conclusions Hyponatremia occurs easily in patient with hepatic cirrhosis and is connected with appearance of ascites with the severily of hepatic function impairment and with serious complications,and therefore is one of the mosy common causes of death.