摘要
Continuous detecting of the rate and size of hematoma expansion is crucial for intracerebral hemorrhage management and treatment. To continuously assess intracerebral hemorrhage in human head, a novel nondestructive microwave head detecting system is presented in this study. An open-ended cylindrical waveguide is employed as sensing antenna, which is operated associated with a coaxial cable for signal transmission and data acquisition. Measurement of amplitude data over the frequency range of 100–400 MHz is processed to evaluate the changes in intracerebral hemorrhage, based on the system's operating principle that the sensor functions as a resonant cavity. Furthermore, 3D printed anatomically and dielectrically realistic human head phantoms with different lesions are fabricated to verify the efficacy of this proposed hemorrhagic stroke assessment system.It is worth noting that the quantitative results show that the system operating in TE_(111) mode is able to detect intracerebral hemorrhage size change as small as 1 cm^3, demonstrating the possibility of this proposed head evaluating system in future preclinical trials.
Continuous detecting of the rate and size of hematoma expansion is crucial for intracerebral hemorrhage management and treatment. To continuously assess intracerebral hemorrhage in human head, a novel nondestructive microwave head detecting system is presented in this study. An open-ended cylindrical waveguide is employed as sensing antenna, which is operated associated with a coaxial cable for signal transmission and data acquisition. Measurement of amplitude data over the frequency range of 100–400 MHz is processed to evaluate the changes in intracerebral hemorrhage, based on the system's operating principle that the sensor functions as a resonant cavity. Furthermore, 3D printed anatomically and dielectrically realistic human head phantoms with different lesions are fabricated to verify the efficacy of this proposed hemorrhagic stroke assessment system.It is worth noting that the quantitative results show that the system operating in TE_(111) mode is able to detect intracerebral hemorrhage size change as small as 1 cm^3, demonstrating the possibility of this proposed head evaluating system in future preclinical trials.
基金
supported by the Scientific and Technological Research Program of Chongqing Municipal Education Commission(Grant No.KJ1704102)
the Doctoral Foundation of Chongqing University of Posts and Telecommunications(Grant No.A2016-77)
