介入化疗栓塞治疗鼻咽癌的临床价值

Clinical Value of Transcatheter Arterial Chemotherapy Embolism in Nasopharyngeal Carcinoma Patients

目的:探讨介入动脉化疗栓塞治疗鼻咽癌的临床价值。方法:将87例鼻咽癌患者分成3组:1)A组(介入化疗+放疗组)26例;2)B组(放疗+化疗组)29例;3)C组(单纯放疗组)32例。结果:随访48-61个月,近期疗效CR分别为A组80.8％、B组58.6％、C组50.0％,A组与B、c组分别比较,差异均有显著性(P<0.05);2、3、4年生存率分别为:A组80.8％、76.9％、61.5％,B组58.6％、51.7％、44.8％,C组46.9％、40.6％、37.5％。结论:采用放疗结合介入化疗栓塞对鼻咽癌治疗有协同作用,值得临床推广应用。

Objective To explore the value of transcatheter arterial chemoembolization (TACE) for nasopharyngeal carcinoma. Methods Eighty-seven cases of nasopharyngeal carcinoma were divided randomized into third groumps:l)A group (transcatheter arterial chemoembolization and radiotherapy), 26 cases.2)B group (radiotherapy and chemotherapy ) ,29 cases.3)C group (simple radiotherapy) ,32 cases. Resi;ts All patients were followed up for 48-61 months.The rates of immediate complete response (CR) of A group,B group and C group were 80.8% and 58.6% and 50.0% respectively (P < 0.05).The A group showed higher 2-,3- and 4-year survival rates than B group and C group with 80.8% ,76.9% ,61.5% and 58.6% , 51.7% ,44.8% and 46.9%,40.6%, 37.5%,respectively (P < 0.01) .Conclusions Radiotherapy plus transcatheter arterial chemotherapy embolism simultaneously for nasopharyngeal carcinoma has synergetic effect, and it needs to be further discussed.