化学发光法检测CA153,CA125,CA199在肺癌及消化道其他肿瘤中的临床意义

Clinical value of CA153,CA125,CA199 of plasma in pulmronary canced and malignant tumor of digestive system by chemilum inescence immuoassay

目的 探讨 CA15 3,CA12 5 ,CA199在肺癌及消化道其他肿瘤测定中的临床价值。 方法 采用化学发光免疫分析法测定健康对照组及患者组血清标本。 结果 肺炎组血清 CA15 3检测结果虽有增加 ,但无统计学意义 :肺癌与肺炎 ,对照组相比较差异显著 (P<0 .0 5 )。胃癌组与胃炎组比较 ,血清 CA12 5 ,CA199检测结果有明显差异 (P<0 .0 5 ,P<0 .0 1) :而消化道其他肿瘤与良性疾病相比较 ,CA12 5 ,CA199均有明显差异 (P<0 .0 5 ,P<0 .0 1)。 结论 血清 CA15 3在肺癌的检测中有临床意义 :血清 CA12 5 ,CA199的检测对肺癌及消化道其他肿瘤都具有重要的临床价值。

Objective To observe diagnosis value of CA153 ,CA125,CA199 in plasma of pulmonary cancers and malignant tumors of digestive tract. Methods Serum CA153, CA125, CA199 of healthy group and patients were assessed by CLIA way. Results Campared with health group alouth, Serum CA153 ofpneumonia increase but it has not significant difference ( P >0.05).Compared with normal group and pneumonia.Serum CA153 of pulmomonary cancor is significant difference ( P <0.05). Compared with gastritis group ,serum CA125 ,CA199 of gastric cancer have important difference (P<0.05,P<0.01) and compared with digestive system benign disease serum CA125,CA199 of digestive sysem neapleasms has significant differenle ( P<0.05, P <0.01). Conclusion Serum CA153 is important in diagnosis of pulmonary cancer. Serum CA125,CA199 are values to diagnosis digestive systerm neoplasms in clinical.