咽炎颗粒的药理作用研究

The Pharmacological Study of Phyaryngitis Granule

目的 :研究咽炎颗粒抗菌抗炎的药理作用。方法 :观察咽炎颗粒体外抑菌和对二甲苯致小鼠耳肿胀的急性炎症 ,大鼠棉球肉芽肿的慢性炎症的作用。了解咽炎颗粒对金色葡萄球菌、流感嗜血杆菌、肺炎链球菌等的作用及急、慢性炎症的影响。结果 :咽炎颗粒对肺炎链球菌、卡他萘瑟氏球菌、流感嗜血杆菌、乙型溶血性链球菌和大肠杆菌等有抑制作用 ;在高剂量组 ,对二甲苯致小鼠耳肿胀的急性炎症有明显抑制作用 (P <0 0 5 ) ;高低剂量组对大鼠棉球肉芽肿的慢性炎症均有明显抑制作用 (P <0 0 5 )。结论

Objective:Theparposeistostudytheanti inflammatoryfunctionandantibacterialeffectofphyaryngitisgranules. Methods:InordertofindouttheactionsofphyaryngitisgranulesonS .Pneumoniae ,N .Caviae,H .influenzae,β hemolyticstreptococcusetal.andtheeffectonacuteandchronicinflammations.AnimalinflammatorymodelwasestablishadbyXyleneto makethemiceearswollenwithanacuteinflammationandgranulationswelling .Results:Theresultshowedthatphyaryngitis granuleshadinhibitiveactiononS.Pneumoniae ,N .Caviae,H .Influenzae ,β hemolyticstreptococcus,etal.Itcouldsigni ficatlyinhibitrasgranulomacausedbycottonroll (P <0 0 5 )andalsoinswellingofearofmousecausedbyXylenefromhigh dosegroup.Conclusion :Thephyaryngitisgranulehadantibioticandanti inflammationfunction .