摘要
对某镍矿进行了恶性肿瘤回顾性队列研究,应调查男职工1959人,失访1人,观察17年,共获得32515.5人年。结果表明,该队列全死因,恶性肿瘤粗死亡率高于一般人群,但差异无显著性。肺癌粗死亡率是24.60/10万(冶炼组是30.09/10万),以全国、会理县男性肺癌死亡专率作参比标准,标化死亡比(SMR)达229.89、975.61,具有统计学意义。肺癌病例从首次接镍作业到肺癌死亡,平均间隔22.3年,肺癌平均死亡年龄54.8岁。本研究结果表明,该矿接触硫化物镍的镍熔炼工肺癌危险度增高。
A retrospective cohort study on maglinant tumor was carried out in a nickel mine.Total of 1959 male workers were investigated and 32515.5 person-year was obtained.Observation period was 17 years.The results showed that all deaths and crude rate of malignant tumor were higher than that in control group, but with no statistical significance.The crude rate of lung cancer in observation group was 24.60/105 (smelting group being 30.09/105). SMRs were 229.89 and 975.61 respectively, compared with the reference population from the Nation and Huili county, showed statistically significant.The latency between first exposure to nickel and the lung cancer appeared was 22.3 years in average; the death age of lung cancer was in mean 54.3 years.The results suggested that nickel smelting workers exposed to nickel sulfide have an excess incidence of lung cancer.
出处
《工业卫生与职业病》
CAS
CSCD
1992年第3期132-135,共4页
Industrial Health and Occupational Diseases
基金
国家"七五"重点科技攻关项目内容
关键词
镍熔炼
流行病学研究
肺肿瘤
镍矿
lung cancer
nickel smelting
epidemiological study
