职业接触汞女工胎盘微量元素含量及其对子代影响的研究

TRACE ELEMENT LEVELS IN PLACENTA OF MERCURY EXPOSED WORKERS AND THE EFFECTS ON THEIR OFFSPRING

本文通过收集职业性接触汞蒸气女工和对照组在分娩时的母体血、脐带血、胎盘和乳汁生物样品,应用原子吸收光谱法测定其汞含量以及胎盘Pb、Mn、Cd、Zn、Fe、Mg、Ca和Se微量元素含量,并随访观察两组子代的生长发育情况。研究结果表明,接触组乳汁、母体血、脐带血和胎盘汞含量均显著高于对照组,表明职业性接汞可使女工体内汞负荷增加,且金属汞易经胎盘转运和乳汁分泌。两组胎盘10种微量元素含量无明显差异。对两组儿童在出生时、生后三个月和生后六个月的随访,其双顶径、身长、体重和胸围没有发现明显差异,表明现有职业性接汞水平对儿童生长发育无明显影响。

Maternal blood, placental tissues, umbilical cord blood and breast milk were collected from 18 pregnant women, among them 9 parturients have occu-pationally exposed to metallic mercury and 9 non-exposed as control. The con-centraitons of inorganic mercury in maternal blood, placental tissues, umbilical cord blood and milk of the exposed group were significantly higher than those of the non-exposed group, strongly indicating the elevation of [mercury burdens of exposed workers and the easy transfer of metallic mercury via placenta and milk. No significant difference was found in the amount of other 10 trace elements (Pb, Mn, Cd, Cr, Cu, Zn, Fe, Mg, Ca,Se) in placentas of the exposed and the non-exposed groups. The growth indexes of babie s were measured in two groups, which indicated that there existed no adverse effect in present exposure level.