辛伐他汀早期干预治疗急性血栓形成性脑梗死的疗效观察

Observation of the curative effect of simvastatin early intervention on acute thrombosis cerebral infarction

目的探讨辛伐他汀早期干预治疗急性血栓形成性脑梗死的临床疗效。方法72例经颅脑CT证实的急性血栓形成性脑梗死患者随机分为两组,治疗组接受辛伐他汀治疗,观察组接受常规治疗,比较两组治疗前后临床神经功能缺损的变化。结果辛伐他汀早期干预治疗急性血栓形成性脑梗死有良好效果,其中基本治愈13例(36.2%)。显著进步14例(38.8%),进步6例(16.7%),总有效率91.7%。未发现明显不良反应。结论辛伐他汀早期干预治疗急性血栓形成性脑梗死安全有效。

Objective:To discuss the curative effect of early intervention with simvastatin on acute throm-bosis cerebral infarction.Methods: 72 patients with acute thrombosis cerebral infarction confirmed by cran-iocerebral CT were divided into two groups randomly,the treatment group received early intervention with simvastatin,the control group received conventional therapy,and then compare the changes of neurological function between two groups.Results: The total effective rate of treatment group(91.7%) was higher than that of the control group(72.2%,P < 0.05).No obvious adverse effects were observed during the course of therapy.Conclusion: Early intervention with simvastatin is an effective and safe treatment for acute throm-bosis cerebral infarction.