瑞芬太尼控制性降压在鼻内镜手术中的临床应用

Clinical application of controlled hypotension induced by remifentanil in nasal endoscopic surgery

目的评价瑞芬太尼持续输注用于静吸复合全麻下鼻内镜手术中控制性降压的效果。方法50例择期鼻内镜手术患者随机分为A组(瑞芬太尼组)和B组(硝普钠组)行控制性降压,观察两组血流动力学变化。结果控制性降压期间两组收缩压、平均动脉压差别不大(P>0.05),A组心率明显低于B组(P<0.05)。结论瑞芬太尼持续输注用于静吸复合全麻下鼻内镜手术中控制性降压可达理想的降压效果,安全可行。

Objective:To evaluate the effect of continuous infusion of remifentanil on controlled hypotension in nasal endoscopic surgery.Methods:50 cases undergoing selective nasal endoscopic surgery were random-ly divided into group A(remifentanil group) and group B(sodium nitroprusside group),and the hemody-namic changes of two groups were compared.Results:There were no not significant different in the systolic blood pressure and mean arterial blood pressure between two groups(P > 0.05).The heart rate of group A was significantly lower than group B(P < 0.05).Conclusion: The continuous infusion of remifentanil had ideal antihypertensive effect in nasal endoscopic surgery,is feasible and safe.