摘要
目的:分析男性不育与体质量指数(BMI)和精液质量间的相互关系。方法:选择本院2015年1月—2018年3月就诊的不育男性患者100例临床资料,参考中国成人BMI标准分为低体质量组(BMI<18.5kg/m^2)、正常组(18.5<BMI<23.9 kg/m^2)、肥胖组(24.0<BMI<27.9 kg/m^2)、重度肥胖组(BMI≥30.0kg/m^2),所有患者均检测精液各质量参数,分析BMI与精液质量间的相关性。结果:与低体质量组和正常组比较,肥胖组和重度肥胖组患者体内雌二醇(E_2)含量最高,睾酮(T)含量降低(P<0.05);通过中位数以及四分位间距分析精液质量各参数发现,正常组精液体积最大,精子总数高于其他3组(P<0.05),余精液质量各参数组间比较未见差异(P>0.05);精液中炎性因子(TNF-α和IL-6)与BMI呈正相关性, VEGF与BMI呈负相关性(P>0.05)。结论:男性BMI与精液质量存在一定关系,当BMI>28时,不育男性T、LH含量明显降低并影响精子活力,临床应引起重视。
Objective:To analyze the correlation between body mass index and semen quality of infertile men.Methods:100 infertile men were selected as subjects from January 2015 to March 2018.According to the difference of body mass index(BMI),the included man were divided into group A(BMI<18.5),group B(18.5<BMI<23.9),group C(24.0<BMI<27.9)and group D(BMI>30.0).All the man were measured the quality parameters of semen.The correlation between the BMI and the quality of semen were analyzed.Results:The level of estradiol(E2)of man in group C or group D was significant higher than that of man in group A or group B,but the level of testosterone(T)were significant lower(P<0.05).The semen volume and total number of sperm of man in group B was highest by analyzing the median and quartile spacing of parameters of semen quality(P<0.05).There was no significant difference in the other parameters of residual semen quality among the four groups(P>0.05).Conclusion:There is a certain correlation between BMI of male body mass index and the quality of semen.When BMI is over 28,the level of T and LH reduce obviously,which can decrease the vitality of sperm.
作者
吴刚峰
朱智荣
骆振刚
唐桂良
应向荣
WU Gangfeng;ZHU Zhirong;LUO Zhengang;TANG Guiliang;YINGXiangrong(Shaoxing People's Hospital,Zhejiang Province,312000)
出处
《中国计划生育学杂志》
2019年第3期327-330,共4页
Chinese Journal of Family Planning
关键词
不育
体质量指数
精液质量
相关性分析
Infertility
Body mass index
Semen quality
Correlation analysis