不孕症女性生殖道病原体感染临床分析

The analysis of laboratory testing of pathogen infection in reproductive tract of infertile women

目的:探讨女性不孕症与生殖道衣原体(CT)、支原体(UU)、淋球菌(NG)病原体感染。方法:选择2016年2月—2017年12月本院接诊的女性不孕症患者125例(不孕组),其中输卵管性不孕61例,非输卵管性不孕64例;另选本院产前检查正常孕妇120例(对照组)。均行生殖道CT、UU、NG检测并分析与不孕症关系。结果:不孕组CT、UU、NG、CT+UU、CT+NG感染率(7.2%、31.2%、4.8%、4.0%、3.2%)均高于对照组(P<0.05),UU+NG交叉感染率与对照组无差异(P>0.05)。输卵管性不孕女性生殖道CT、UU、NG、CT+UU、CT+NG感染率(13.1%、49.2%、9.8%、8.2%、6.6%)均高于非输卵管性不孕女性(P<0.05),UU+NG交叉感染率与非输卵管性不孕组无差异(P>0.05)。CT、UU、NG、CT+UU、CT+NG、UU+NG感染与女性输卵管性不孕具有相关性(P<0.05)。结论:女性生殖道CT、UU、NG感染和交叉感染可增加女性不孕症的患病风险,尤其是交叉感染育龄期女性,临床应重视对女性不孕症患者上述指标检测。

Objective:To explore the infection of chlamydia gonorrhoeae(CT),ureaplasma urealyticum(UU),and neisseria gonorrhoeae(NG)in the reproductive tract of infertile women.Methods:125 infertile women were selected in this study from February 2016 to December 2017,which included 61 women with tubal infertility(group A)and 64 women without tubal infertility(group B),and other 120 normal pregnant women were selected in group C.All the women were examined by CT,UU and NG,and the relationship between the rate of CT,UU,and NG infection and the rate of female infertility was analyzed.Results:The infection rates of CT,UU,NG,CT+UU and CT+NG of women in group A and B were 7.2%,31.2%,4.8%,4.0%,and 3.2%,respectively,which were all significant higher than those of women in group C(P<0.05),but the rate of UU+NG infection had no significant different between infertile women and normal pregnant women(P>0.05).The infection rates of CT,UU,NG,CT+UU,CT+NG of women in group A were 13.1%,49.2%,9.8%,8.0%,and 6.6%,respectively,which were all significant higher than those of women in group B(P<0.05),but the rate UU+NG infection had no significant different between group A and B(P>0.05).CT,UU,NG,CT+UU,CT+NG,and UU+NG infection were associated with tubal infertility of women(P<0.05).Conclusion:The CT,UU,NG infection in female reproductive system maybe increase the risk of female infertility,especially the reproductive age women with multiple infection by CT,UU and NG,so the monitoring of CT,UU,NG infection of female infertility should be paid more attention to.