6620例早、中期妊娠妇女不同年龄段全血微量元素分析

Analysis of blood trace elements levels of pregnancy women with different age during the first and second trimester pregnancy

目的:探讨不同妊娠期不同年龄孕妇微量元素的全血含量,为孕妇合理安全补充微量元素提供依据。方法:6620例年龄20~39岁健康孕妇,按孕期分为早孕组2530例和中孕组4090例。分别进行血铜、锌、钙、镁、铁含量检测,选取相同年龄范围200例健康非妊娠妇女作对照组。结果:在早、中孕期,孕妇血镁、钙水平与对照组无统计学差异(P>0.05),铜高于对照组(P<0.05),锌、铁低于对照组(P<0.05)。早、中孕期26~<36岁及≥36岁年龄段血铜水平高于≤25岁年龄段(P<0.05),孕中期≤25岁段血铁水平高于26~<36岁及≥36岁年龄段妇女(P<0.05)。早孕、中孕组血铁低水平比率分别为16.1%和27.8%,与对照组(1.5%)比较有统计学差异(P<0.01);早孕、中孕期分别有5.8%、9.6%的孕妇血锌水平低,高于对照组(2.5%)(P<0.01)。早中孕期妇女血钙低水平分别占4.97%和4.96%,高于对照组(2.5%)(P<0.05)。结论:宜根据孕妇不同孕期不同年龄阶段补充微量元素,以满足母亲和胎儿的需要。

Objective:To investigate the blood trace elements levels of pregnancy women with different age during the first and second trimester pregnancy,and to provide evidences for the reasonable and safe supplementation of trace elements of pregnant women.Methods:6620 health pregnant women aged 20-39 years were divided into group A(2530 cases during the first trimester pregnancy)and group B(4090 cases during the second trimester pregnancy),and other 200 health women without pregnancy were selected in group C.The blood copper,zinc,calcium,magnesium and iron of all included women were tested.Results:There were no significant different in the blood calcium and magnesium between pregnant women and non-pregnant women(P>0.05),but the blood copper level of women in group A and B was significantly higher than that of women in group C,and the levels of blood zinc and iron in group A and B were significant lower than those of women in group C(P<0.05).In group A and B,the blood copper level of women with 26-36 years old and≥36 years old were significant higher than that of women with≤25 years old(P<0.05).In group B,the blood iron level of women with 26-36 years old and≥36 years old were significant lower than that of women with≤25 years old(P<0.05).The rate of low iron level of women in group A and B was 16.1%and 27.8%,respectively,which was significant different from that of women in group C(P<0.01).The rate of low zinc level of women in group A and B was 5.8%and 9.6%,respectively,which was significant different from that of women in group C(P<0.01).The rate of low calcium level of women in group A and B was 4.97%and 4.96%,respectively,which was significant different from that of women in group C(P<0.05).Conclusion:In order to meet the needs of mothers and fetuses,it should be supplemented trace elements according to the characteristics of different trace elements levels of pregnant women in different ages during different pregnant stage.