摘要
合成了一种含有聚酰胺胺链段的聚(醚—酰胺胺—脲—氨酯)(PEAUU)嵌段共聚物。这种嵌段共聚物较诸相应的聚酰胺胺,有较好的机械性能和对稀酸、稀碱以及生理盐水的良好稳定性。体外试验表明,它本身就具有良好的抗凝血性,经过肝素处理,PEAUU表面与肝素形成了聚电解质复合物,抗凝血性能又有进一步提高。
A block copolymer of poly(ether--amidoamine-urea-urethane)(PEAUU) con-taining polyamidoamine segment was synthesized. This block copolymer possesses im-proved mechanical properties and far more resistant toward hydrolytic degradation ofdilute acid and base as compared to polyamidoamine. vitro tests demonstrated,PEAUU itself, and especially after heparinization, has excellent blood anticoagulatingproperty.
出处
《功能高分子学报》
CAS
CSCD
1992年第4期292-298,共7页
Journal of Functional Polymers
关键词
聚酰胺胺
PEAUU
肝素化
抗凝血药
poly amidoamine
poly (ether-amidoamine-urea-urethan)
block copolymer
heparinization
blood anticoagulating
