多元化干预对肾病综合征患者治疗疗效、焦虑抑郁情绪及生活质量的影响

Effects of diversified intervention on treatment efficacy,anxiety,depression and quality of life in patients with nephrotic syndrome

目的:探讨多元化干预对肾病综合征患者治疗疗效、焦虑抑郁情绪及生活质量的影响。方法:选取2016年5月至2017年5月我院收治的150例肾病综合征患者作为研究对象,回顾性分析所有患者的病例资料,根据不同干预方式分为两组,分别为对照组(75例)和观察组(75例),对照组患者在临床上给予常规干预,观察组患者采取多元化干预治疗,两组患者均干预半个月,治疗结束后对比两组患者治疗前后焦虑抑郁情绪及生活质量、临床疗效的变化。结果:观察组患者治疗缓解率明显高于对照组(χ~2=6.000,P=0.014);治疗前,两组患者的抑郁及焦虑评分组间差异无统计学意义;治疗后,两组患者的抑郁及焦虑评分均降低,且观察组治疗后抑郁及焦虑评分降低程度均明显大于对照组(t=2.951,9.553;P<0.01);干预前,两组患者SF-36生活质量量表中自身健康状况、生活活力及社会关系、情感职能、精神健康得分水平均无明显差异;干预后,两组患者在自身健康状况得分水平无明显差异,然而两组干预后的自身健康状况、生活活力及社会关系、情感职能、精神健康得分水平均较干预前有明显差异,具有统计学意义(P<0.05),在生活活力及社会关系、情感职能、精神健康得分水平较干预前均显著升高,差异具有统计学意义(t=7.014,11.665,7.935,6.645;P<0.001)。结论:对肾病综合征患者,相比常规的临床干预治疗,在临床上采取多元化干预的治疗效果更理想,有效的控制了患者的焦虑抑郁的不良情绪,提高了患者的生活质量。

Objective:To investigate the effect of diversified interventions on the treatment efficacy,anxiety and depression and quality of life in patients with nephrotic syndrome.Methods:A total of 150 nephrotic syndrome patients admitted to our hospital from May 2016 to May 2017 were selected as the research object,and the data of all the patients were retrospectively analyzed.According to different interventions,they were divided into control group(75cases)and observation group(75cases).Patients in the control group were given routine interventions in the clinic.Patients in the observation group were treated with multiple interventions,and both groups were intervened for half a month.The anxiety and depression,the quality of life and the clinical effect of the(下转第382页)two groups before and after treatment were compared.Results:The response rate(96.00%)in the observation group was significantly higher than that in the control group(84.00%)(χ~2=6.000,P<0.05).Before treatment,there was no significant difference between the two groups in the scores of depression and anxiety.After treatment,the scores of depression and anxiety in both groups were lower than those in the control group(t=3.117,2.998,13.172;P<0.01).After treatment,the depression and anxiety scores of the two groups were decreased.The depression and anxiety scores in the observation group were significantly lower than those in the control group(t=2.951,P<0.01);Before the intervention,there were no significant differences in self-health status,life activity,social relationship,emotional function,mental health score between the two groups.There was no significant difference between the two groups in the scores of their own health status after intervention,However,their own health status,life vitality and social relations,emotional function and mental health score after intervention were significantly higher than those before intervention,which was statistically significant.The scores of life vitality,social relations,emotional functions and mental health were significantly higher than those before intervention(t=7.014,11.665,7.935,6.645;P <0.001).Conclusion:In patients with nephrotic syndrome,the effectiveness of diversified interventions in clinical practice is better than that of routine clinical nursing interventions.It effectively controls the patients’ anxiety and depression-inducing feelings and improves their quality of life.