系统性心理干预对伴焦虑抑郁消化性溃疡患者心理状态和生活质量的影响

Effect of systemic psychological intervention on mental status and quality of life in patients with peptic ulcer associated with depression and anxiety disorders

目的:探讨系统性心理干预对伴焦虑抑郁消化性溃疡患者心理状态和生活质量的影响。方法:选取2014年1月至2016年10月我院收治的98例伴焦虑抑郁消化性溃疡患者作为研究对象,采用回顾性分析法分析所有患者的临床资料,按照资料中其治疗方法将147例患者分为对照组40例和研究组58例,对照组患者在所患疾病临床治疗上予以常规干预及健康教育,研究组在对照组基础上予以系统性心理干预,两组患者均干预8周,干预结束后比较两组患者负性情绪及生活质量的变化情况,并对两组患者幽门螺旋杆菌清除率、溃疡愈合和1年后复发情况进行统计分析。结果:①两组患者干预后其SAS、SDA评分均较干预前降低,且研究组降低程度明显大于对照组,比较差异具有统计学意义(t=4.976,6.155;P<0.001);②两组患者干预后生活质量评分较干预前明显升高,且研究组升高程度明显大于对照组(P<0.05);③研究组溃疡愈合、幽门螺杆菌清除率明显高于对照组,1年后复发率明显低于对照组,数据差异具有统计学意义(χ~2=11.064,10.271,9.035;P<0.01)。结论:系统性心理干预对伴焦虑抑郁消化性溃疡患者可明显减轻患者焦虑和抑郁程度,提高生活质量,降低复发率,为临床上提高伴焦虑抑郁消化性溃疡患者的诊治水平提供了参考依据。

Objective:To investigate the effect of systemic psychological intervention on mental status and quality of life in patients with peptic ulcer associated with depression and anxiety disorders.Methods:The clinical data of 98 peptic ulcer patients associated with depression and anxiety disorders admitted in our hospital from January 2014 to October 2016 were retrospectively analyzed.All patients received the clinical symptomatic treatment,and based on this,40 patients in the control group were given routine intervention and health education,58 patients in the study group were given systemic psychological intervention on the basis of therapeutic schedule of control group,both tid for 8 wk.The changes of negative emotion and quality of life in two groups were compared.The Helicobacter pylori(Hp)clearance rate,ulcer healing and recurrence after 1 years in two groups of patients were statistically analyzed.Results:①The SAS and SDA scores of the two groups were decreased,and the decreasing level was more obvious in the study group than in the control group(t=4.976,6.155;P<0.001);②The quality of life scores of two groups were significantly increased,and the increasing level was more obvious in the study group than in the control group(P<0.05);③The ulcer healing and Hp eradication rate in the study group were significantly higher than those in the control group,and the recurrence rate after 1 year was significantly lower than that in the control group(χ~2=11.064,10.271,9.035;P<0.01).Conclusion:The systemic psychological intervention can significantly reduce anxiety and depression degree and the recurrence rate,improve quality of life,and provide a reference for the diagnosis and treatment of peptic ulcer associated with depression and anxiety disorders.