摘要
目的:比索洛尔配合步行运动训练对充血性心力衰竭(CHF)患者心功能、负性情绪及生活质量的影响。方法:回顾性分析2014年6月-2017年6月收治的100例CHF患者临床资料,根据治疗方法分为观察组(n=50)和对照组(n=50)。对照组应用常规治疗和步行运动训练,观察组在对照组基础上加用比索洛尔。评估治疗前、治疗6个月后心功能[左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)]、步行距离[6min步行距离(6MWD)]、负性情绪[简明心境状态量表(POMS)]、生活质量[明尼苏达心力衰竭生活质量量(MLHFQ)]。结果:①治疗6个月后,两组LVEF均高于治疗前(t=-17.719,-11.209;P<0.05),两组LVEDD、LVESD均低于治疗前(t=11.602,6.474;P<0.05),观察组变动幅度均大于对照组(t=11.583,7.483;P<0.05);②治疗6个月后,两组6MWD均高于治疗前(t=-11.033,-6.522;P<0.05),观察组增幅大于对照组(t=4.102,P<0.05);③治疗6个月后,两组紧张、愤怒、疲劳、抑郁、慌乱得分均低于治疗前(P<0.05),精力、和自尊感得分均高于治疗前(P<0.05),观察组变动幅度大于对照组(P<0.05);④治疗6月后,两组MLHFQ得分均低于治疗前(t=11.571,9.408;P<0.05),观察组降幅大于对照组(t=-2.580,P<0.05)。结论:比索洛尔配合步行运动训练有利于改善CHF患者心功能、负性情绪及生活质量,临床应用价值较大。
Objective:To explore the effects of bisoprolol combined with walking exercise training on cardiac function,negative emotions and quality of life in patients with congestive heart failure(CHF).Methods:The clinical data of 100 patients with CHF admitted between June 2014 and June 2017 were retrospectively analyzed.According to the treatment methods,they were divided into observation group(n=50)and control group(n=50).Control group was given routine treatment and walking exercise training,and observation group was given bisoprolol on the basis of control group.The cardiac function[left ventricular ejection fraction(LVEF),left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD)],walking distance[6 min walking distance(6 MWD)],negative emotions[Profile of Mood States(POMS)]and quality of life[Minnesota Living with Heart Failure Questionnaire(MLHFQ)]were assessed before treatment and after 6 months of treatment.Results:After 6 months of treatment,the LVEF in the two groups was higher than that before treatment(t=-17.719,-11.209;P<0.05),and the LVEDD and LVESD were lower than those before treatment(t=11.602,6.474;P<0.05),and the changes in observation group were higher than those in control group(t=11.583,7.483;P<0.05).After 6 months of treatment,the 6 MWD in the two groups was higher than that before treatment(t=-11.033,-6.522;P<0.05),and the increase in observation group was greater than that in control group(t=4.102,P<0.05).After 6 months of treatment,the scores of tension,anger,fatigue,depression and confusion in the two groups were lower than those before treatment(P<0.05),and the scores of energy and self-esteem were higher than those before treatment(P<0.05),and the changes in observation group were greater than those in control group(t=-5.991,-3.121,-5.458,-11.141,5.388,-3.747,3.547;P<0.05).After 6 months of treatment,the MLHFQ scores in the two group were lower than those before treatment(t=11.571,9.408;P<0.05),and the decrease in observation group was greater than that in control group(t=-2.580,P<0.05).Conclusion:Bisoprolol combined with walking exercise training is beneficial to improve cardiac function,negative emotions and quality of life in patients with CHF,and it has great clinical application value.
作者
朱小琴
邓仁生
陈胜媚
ZHU Xiaoqing;DENG Rensheng;CHEN Shengmei(Hubei Enshi Tujia and Miao Autonomous Prefecture Central Hospital,Enshi 445000,China)
出处
《中国健康心理学杂志》
2019年第9期1362-1365,共4页
China Journal of Health Psychology
基金
湖北省自然科学基金(编号:2017CFB147)