乌司他丁治疗重度脓毒血症临床观察

Clinical observation of Ulinastatin in the treatment of severe sepsis

目的:对乌司他丁治疗重度脓毒血症临床疗效进行观察研究。方法:随机选取2014年5月至2015年5月时间范围本院接收的50例重度脓毒血症患者,将其划分为研究组与对照组,各25例,对照组接受常规临床治疗,研究组在对照组基础上接受乌司他丁治疗,就两个组别的临床疗效进行观察对比。结果:研究组平均住院时长、好转率相较于对照组显著不同,研究组治疗后1d、3d、5dapaCheii评分相较于对照组显著更低,数据差异具备统计学意义(p<0.05)。结论:乌司他丁应用于治疗重度脓毒血症疗效满意,可有效缓解患者痛苦,安全可靠,具备临床借鉴普及意义。

Objective:Observe the clinical effect of Ulinastatin in the treatment of severe sepsis.Methods:Randomly select 50 cases of severe sepsis patients the hospital received from May 2014 to May 2015,divided into study group and control group,25 cases in each,the control group received routine clinical care,the research group received Ulinastatin treatment on the basis of routine clinical care,the clinical effect of two groups were observed and compared.Result:The research group’s average hospitalization time,improvement rate were significantly different compared with the control group,after the treatment of 1d,3d,5dAPACHEII score of the study group compared to the control group was significantly lower,the differences in the data with statistical significance(P<0.05).Conclusion:Curative effect of Ulinastatin in the treatment of severe sepsis was satisfied,which can effectively alleviate the suffering of patients,safe and reliable,have clinical use of reference.