摘要
目的:探究左旋多巴对帕金森病人的负面影响。方法:调阅2014年1月-2016年3月在我院接受帕金森疾病治疗的60例患者的临床资料,将其中30例接受左旋多巴治疗的患者作为a组,未接受左旋多巴治疗的另外30例患者作为B组,30例同期来院接受健康体检者作为C组,检测三组人员的血浆叶酸、维生素B12和hCy(同型半胱氨酸)水平,并分析比较。结果:a患者的血浆hCy含量显著高于B、C组。结论:帕金森患者的病情发展与高含量的血浆hCy密切相关,所以,要及时检测接受左旋多巴治疗的帕金森患者的血浆叶酸、维生素B12和hCy水平,应加强抗帕金森临床用药的监管工作,做到合理用药。
Objective:To explore the negative effects of levodopa on patients with Parkinson’s disease.Methods:Access to January 2014 to 2016 years 3 months in our hospital accepted the clinical data of 60 patients with Parkinson’s disease treatment,the 30 cases received levodopa treated patients as a group,did not receive the treatment of levodopa in another 30 cases of patients as group B,30 cases in the hospital at the same time to accept the health examination persons as group C,personnel in the three groups were detected plasma folate,vitamin B12,and homocysteine(Hcy)level,and comparative analysis.Result:The plasma Hcy levels in A patients were significantly higher than those in B and C groups.Conclusion:Is closely related to the progression of Parkinson’s patients with high levels of plasma Hcy,therefore,to timely check and accept of levodopa therapy in Parkinson’s patients plasma folate,vitamin B12,and homocysteine levels,should strengthen the supervision of the clinical use of anti Parkinson’s,to achieve rational use of drugs.
出处
《健康之路》
2016年第3期6-6,共1页
Health Way
