期刊文献+

顺铂不同给药途径联合紫杉醇治疗晚期卵巢癌的疗效对比 被引量:1

原文传递
导出
摘要 目的:对比分析顺铂不同给药途径联合紫杉醇治疗晚期卵巢癌的疗效。方法:选取2014年9月~2016年9月我院收治的晚期卵巢癌患者80例,随机分为观察组与对照组,各40例,观察组采用腹腔灌注顺铂联合紫杉醇治疗,对照组采用静脉滴注顺铂联合紫杉醇治疗。结果:观察组卵巢癌晚期治疗有效率(77.5%)显著高于对照组(57.5%)(P<0.05)。在不良反应方面,除骨髓抑制外,观察组胃肠道反应、肝肾毒性、神经毒性和肌肉关节痛发生率显著高于对照组(P<0.05)。结论:采用腹腔灌注顺铂联合紫杉醇治疗晚期卵巢癌疗效较静脉滴注顺铂联合紫杉醇疗效更好,且患者对不良反应耐受性较好,值得进一步研究和推广。
作者 冯艳玲
出处 《健康之路》 2016年第12期85-86,共2页 Health Way
  • 相关文献

参考文献3

二级参考文献29

  • 1曹泽毅.中华妇产科学[M].北京:人民卫生出版社,1999.2129.
  • 2Siegel R ,Naishadham D, Jemal A. Cancer statistics ,2012 [ J ]. CA Cancer J Clin,2012,62( 1 ) :10 -29.
  • 3Hennessy BT,Coleman RL,Markman M. Ovarian cancer[ J]. Lan- cet,2009,374 (9698) : 1371 - 1382.
  • 4Vergote I, Trop CG, Amant F, et al. Neoadjuvant chemotherapy or primary surgery in stage IIIc or IV ovarian cancer [ J ]. N Engl J Med,2010,363 (10) :943 -953.
  • 5King MC, Marks JH, Mandell JB. Group TNYBCS, for the New York Breast Cancer Study Group. Breast.and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2 [ J]. Science, 2003,302:643 - 646.
  • 6Panici PB, Maggioni A, Hacker N, et al. Systematic aortic and pel- vic lymphadenectomy versus resection of bulky nodes only in opti- mally debulked advanced ovarian cancer:a randomized clinical trial [J]. J Natl Cancer Inst,2005,97:560 -566.
  • 7Aletti GD, Gostout BS, Pedratz KC, et al. Ovarian cancer surgical resectability: relative impact of disease, patient status, and surgeon [ J]. Gynecol Ouco1,2006 ,100 :33 - 34.
  • 8du Bois A,Reuss A,Pujade - Lauraine E,et al. Role of surgical outcome as prognostic factor in advanced epithelial ovarian cancer: a combined exploratory analysis of 3 prospectively randomized phase 3 muhicenter trials: by the Arbeitsgemeinschaft Gynaekolo- gische Onkologie Studiengruppe Ovarialkarzinom (AGO -OVAR) and the Groupe d "Investigateurs Nationaux Pour les Etudes des Cancers de l'Ovaire ( GINECO ) [ J ]. Cancer, 2009,115 : 1234 - 1244.
  • 9Trimbos JB, Parmar M, Vergote I, et al. International Collaborative Ovarian Neoplasml, and the European Organisation for Research and Treatment of Cancer Collaborators - Adjuvant Chemotherapy un Ovarian Neoplasm. International Collaborative Ovarian Neoplasm trial 1 and Adjuvant Chemotherapy In Ovarian Neoplasm trial:two parallel randomized phase III trials of adjuvant chemotherapy in pa- tients with early -stage ovarian carcinoma[ J]. J Natl Cancer Inst,2003,95:105 - 111.
  • 10Kehoe S. Second look laparotomy and ovarian cancer [ J ]. J Surg Oncol, 1994,57:205.

共引文献82

同被引文献10

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部