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抗环瓜氨酸肽(CCP)抗体检测对早期类风湿关节炎的诊断价值探讨 被引量:2

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摘要 目的:重点研究抗环瓜氨酸肽抗体检测用于诊断早期类风湿关节炎的临床价值。方法:收集本院2015年1月到2016年12月共收治类风湿性关节炎患者45名(观察组),非类风湿性关节炎患者42名(对照组),对两组患者的血清样本进行检测,分析患者抗环瓜氨酸肽(CCP)抗体的阳性比例以及平均浓度。并且将类风湿因子(RF)检测方法作为对比分析。结果:观察组45名患者当中抗环瓜氨酸肽(CCP)抗体阳性有39例,平均浓度为54.8RU/ml,类风湿因子(RF)阳性41例;对照组患者抗环瓜氨酸肽(CCP)抗体阳性有3例,平均浓度为8.2RU/ml,类风湿因子(RF)15例。两组患者在阳性例数与平均浓度上有显著差异(P<0.05)。结论:抗环瓜氨酸肽(CCP)抗体检测对早期类风湿关节炎患者的诊断具有临床价值,并且可以有效的提高诊断准确性。
出处 《健康之路》 2017年第6期10-10,共1页 Health Way
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  • 1康闽,王宏伟,程佩萱,施虹.抗环瓜氨酸肽抗体在幼年特发性关节炎诊断中的意义[J].中国实用儿科杂志,2006,21(6):446-448. 被引量:7
  • 2伊心浩,朱新兴,张旗,刘东,杨琴.血清葡萄糖-6-磷酸异构酶与自身免疫性疾病相关性研究[J].检验医学,2007,22(2):182-184. 被引量:8
  • 3Berent P, Albani S, Alberto M. Juvenile idiopathic arthritis [ J ]. Lancet, 2011,377(9783) :2138 -2149,.
  • 4Rojas - Serrano J,Burgns - Vargas R,Perez LL,et at. Very recent onset arthritis:The value of initial rheumatologist evaluation and anti - cyclic eitrullinated peptide antibodies in the diagnosis of rheumatoid arthritis [ J]. Clin Rheumatol,2009,28 (10) : 1135 - 1139.
  • 5Gupta R, Thabah MM, Vaidya B, et al. Anti - cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis[ J]. Indian J Pediatr,2010,77 (1) .41 -44.
  • 6Kuna AT, Lamot L, Miler M,et al. Antibodies to mutated eitrullinated vi- mentin and antibodies to cyclic citrullinated peptides in juvenile idio- pathic arthritis[ J]. Clin Chem Lab Meal,2009,47 ( 12 ) : 1525 - 1530.
  • 7Petty RE, Southwood TR, Manners P, et al. International. league of asso- ciations for rheumatology classification of juvenile idiopathic arthritis: Second revision, edmonton,2001 [ J ]. J Rheumatol,2004,31 ( 2 ) : 390 - 392.
  • 8Aletaha D, Neogi T, Silman AJ, et al. 2010 rheumatoid arthritis classifi- cation criteria : An American college of rheumatology/european league a- gainst rheumatism collaborative initiative [ J ]. Arthritis Rheum, 2010,62 (9) :2569 -2581.
  • 9Svord A, Kastbom A, Ssdedin MK, et al. A comparison between IgG - and IgA - class antibodies to cyclic citrullinated peptides and to modi- fied citrullinated vimentin in early rheumatoid arthritis and very early arthritis [J]. J Rheumatol,2011,38(7) :1265 - 1272.
  • 10Gilliam BE, Reed MR, Chauhan AK,et al. Evidence of fibrinogen as a target of citrullination in IgM rheumatoid factor - positive polyarticu- lar juvenile idiopathic arthritis[ J]. Pediatr Rheumatol Online J,2011, 9:8.

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