孕早期超声测量胎儿颈项透明层厚度在产前诊断中的应用价值探讨

Application of Ultrasonography in the Diagnosis of Fetal Neck Transparent Layer Thickness in Prenatal Diagnosis

目的:观察并探讨孕早期超声测量胎儿颈项透明层厚度在产前诊断中的临床应用价值。方法:选取我院2015年10月—2016年10月期间收治的118例进行孕早期超声测量系统性产前超声筛查的单胎孕妇,实验组胎儿(59例)颈项透明层厚度<2.5mm,对照组胎儿(59例)颈项透明层厚度≥2.5mm,对所有胎儿进行头臀径、静脉导管血流频谱以及颈项透明层厚度等项目的检查,并对胎儿颈项透明层厚度≥2.5mm的孕妇给予的晚期超声复查,观察并对比两组胎儿颈项透明层厚度与异常妊娠之间的关系。结果:对照组胎儿异常妊娠发生率为71.18%,实验组胎儿异常妊娠发生率为6.77%,实验组胎儿的异常妊娠发生率显著低于对照组,P<0.05,差异具有统计学意义;胎儿颈项透明层厚度的增加与异常妊娠发生率呈现出正相关性。结论:孕早期超声测量胎儿颈项透明层厚度在产前诊断中具有显著的应用价值,颈项透明层厚度与异常妊娠发生率具有相关性,值得在临床上推广应用。

Objective:To observe and explore the clinical value of ultrasonography in measuring the thickness of fetal neck in the diagnosis of prenatal diagnosis.Methods:A total of 118 pregnant women were enrolled in our hospital from October 2015 to October 2016.The experimental group of fetuses(59 cases)had a transparent layer thickness of<2.5 mm.,The control group of fetal(59 cases)neck transparent layer thickness≥ 2.5 mm,for all the fetus head and hip diameter,venous catheter flow spectrum and neck thickness of the transparent layer,and the fetal neck transparent layer thickness≥ 2.5 mm pregnant women given Advanced ultrasound review,observation and comparison between the two groups of fetal neck transparent layer thickness and the relationship between abnormal pregnancy.Result:The incidence of abnormal pregnancy was 71.18%in the control group and 6.77%in the experimental group.The incidence of abnormal pregnancy was significantly lower in the experimental group than that in the control group(P<0.05).The difference was statistically significant.The increase in layer thickness showed a positive correlation with the incidence of abnormal pregnancy.Conclusion:The thickness of transparent layer of fetal neck in early pregnancy has significant application value in prenatal diagnosis.The thickness of transparent layer of neck is related to the incidence of abnormal pregnancy and is worthy of clinical application.