糖尿病肾病患者行阿托伐他汀钙片联合阿魏酸哌嗪片治疗的应用价值

The application value of the treatment of the atorvastatin calcium tablets combined with the treatment of alwei piperazine tablets in patients with diabetic nephropathy

目的:分析糖尿病肾病患者行阿托伐他汀钙片联合阿魏酸哌嗪片治疗的应用价值。方法:随机抽取2016年3月到2017年3月本院收治的122例糖尿病肾病患者作为研究对象,根据不同的治疗方法将其分对照组(n=61)与治疗组(n=61)。对照组给予阿魏酸哌嗪片治疗,治疗组给予阿托伐他汀钙片联合阿魏酸哌嗪片治疗,对比分析两组血脂水平、血清炎性因子、代谢指标水平、肾间质纤维化指标水平、临床治疗有效率、不良反应发生率。结果:治疗组各项血脂水平指标明显优于对照组,且临床治疗有效率明显高于对照组,P<0.05;同时两组患者均出现腹胀、腹痛等不良反应,停药两天后不良反应均自行消失,组间对比差异不明显,P>0.05。结论:在糖尿病肾病患者的临床治疗中,行阿托伐他汀钙片联合阿魏酸哌嗪片治疗,临床疗效显著,对改善患者临床症状及实验室指标具有积极作用,同时不良反应经处理后可自行消失,安全性较高,值得临床推广应用。

Objective:To analyze the value of atorvastatin calcium tablets combined with ferulic acid piperazine tablets in patients with diabetic nephropathy.Methods:A total of 122 patients with diabetic nephropathy were enrolled in this study from March 20 to March 2017.The patients were divided into control group(n=61)and treatment group(n=61)according to different treatment methods.The rats in the treatment group were treated with atorvastatin calcium supplementation and ferulic acid piperazine tablets.The levels of serum lipids,serum inflammatory factors,metabolic indexes,renal interstitial fibrosis The level of indicators,the effectiveness of clinical treatment,the incidence of adverse reactions.Result:The levels of blood lipid in the treatment group were significantly better than those in the control group,and the effective rate of clinical treatment was significantly higher than that of the control group(P <0.05).At the same time,adverse reactions such as abdominal distension and abdominal pain occurred in both groups.Self-disappeared,the difference between groups was not significant,P> 0.05.Conclusion:The treatment of patients with diabetic nephropathy,the treatment of atorvastatin calcium tablets combined with ferulic acid piperazine tablets,the clinical efficacy of significant,to improve the clinical symptoms and laboratory indicators have a positive effect,while the adverse reactions after treatment Can be self-disappearing,high security,worthy of clinical application.