布地奈德联合特布他林雾化吸入辅助治疗小儿支气管哮喘的药学价值分析

The pharmacological value analysis of the treatment of children bronchial asthma by budesonide united tebutamine atomization inhalation

目的:探讨布地奈德联合特布他林雾化吸入辅助治疗小儿支气管哮喘的药学价值。方法:选择2015年7月-2017年7月在我院接受治疗的小儿支气管哮喘患者共106例,将其依据随机分配法分为对照组和治疗组,每组53例。对照组采用布地奈德混悬液雾化吸入治疗,治疗组在采用布地奈德的基础上联合特布他林与生理盐水雾化吸入治疗,比较两组患儿治疗效果、症状消退时间、肺功能。结果:在本次研究中,治疗后,与对照组相比,治疗组FEV1和PEF占预计值都明显升高,(P<0.05)。治疗组呼吸急促消退时间、哮鸣音消退时间、咳嗽消退时间均比较短,(P<0.05)。对照组总有效率为77.36%,治疗组总有效率为96.23%,治疗组总有效率明显高于对照组,(X2=8.2298,P<0.05)。结论:经过研究,对支气管哮喘患儿,采用布地奈德联合特布他林雾化吸入有着确切的效果,能够有效改善患儿的肺功能,同时缩短症状消退时间,起效更快,不良反应发生率低,值得在临床中应用。

Objective:To investigate the pharmacological value of budesonide combined with terbutaline in the treatment of bronchial asthma in children.Methods:A total of 106 children with bronchial asthma who underwent treatment in our hospital from July 2015 to July 2017 were divided into control group and treatment group according to random assignment method.The control group was treated with aerosolized inhalation of budesonide suspension.In the treatment group,the combination therapy of terbutaline and physiological saline was treated in combination with budesonide.The therapeutic effect,symptom subsided time and lung Features.Result:In this study,the levels of FEV1 and PEF in the treatment group were significantly higher than those in the control group(P <0.05).The rate of wheezing,the time of wheeze subsided and the time of coughing were shorter(P<0.05).The total effective rate was 77.36%in the control group and 96.23%in the treatment group.The total effective rate in the treatment group was significantly higher than that in the control group(X2 = 8.2298,P <0.05).Conclusion:After the study,the use of budesonide combined with terbutaline inhalation has a definite effect on children with bronchial asthma,which can effectively improve the lung function of children and shorten the time of symptom subsidence,The incidence is low,it is worth in clinical application.