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一氧化氮及一氧化氮合酶与骨质疏松 被引量:3

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摘要 一氧化氮(NO)是体内重要的信号分子和效应分子,一氧化氮合酶(NOS)是NO合成的限速酶。在骨组织中,由骨细胞产生的NO可通过自分泌或旁分泌方式影响骨重建。病理条件下,NO异常分泌可使骨形成与骨吸收失平衡,这与骨质疏松的发病密切相关,因此药物调节NO量成为探索治疗骨质疏松症的新途经之一。
作者 孟健
出处 《国外医学(内分泌学分册)》 2003年第2期127-129,共3页 Foreign Medical Sciences(Section of Endocrinology)
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参考文献18

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同被引文献21

  • 1邢倩,苏本利,李昌臣,杜建玲,白然,张嘉宁,许朝晖.内皮型一氧化氮合酶基因多态性与2型糖尿病肾病相关[J].中华内分泌代谢杂志,2004,20(5):435-437. 被引量:6
  • 2张政,彭惠民,张素华,郭风劲,晏宁.iNOS基因微卫星多态性与中国汉族人群糖尿病肾病相关[J].中华内分泌代谢杂志,2004,20(6):527-528. 被引量:4
  • 3张大威,程岩,张金超,王乃利,杨梦甦,姚新生.淫羊藿苷对破骨细胞的分化及骨吸收功能的影响[J].中国药理学通报,2007,23(4):463-467. 被引量:73
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