针刺治疗血液流变学异常偏头痛的临床研究

Investigation of acupuncture on the treatment of migraine with abnormal hemorrheology

目的 观察针刺治疗血液流变学异常偏头痛的临床疗效及治疗前后血液流变学指标的改变。方法 将 10 0例血液流变学异常偏头痛患者辨证分为 5型取穴施治。分别于针刺治疗前后进行症状学和检验学总评分及血液流变学指标测定 ,并比较。结果 本组 10 0例 ,临床总有效率 95 % ;针刺治疗前后症状学和检验学总评分分别为 ( 13 .76± 3.6 5 )分和 ( 9.6 8± 2 .37)分 ,治疗前后比较有极显著性差异 (P <0 .0 1) ,血液流变学指标全血高切黏度、全血低切黏度、血浆黏度、血浆纤维蛋白原治疗后比治疗前均明显降低 ( P <0 .0 5或P <0 .0 1)。结论 针刺治疗血液流变学异常偏头痛疗效确切 ,且针刺治疗能改善血液流变学的多项指标 ,提示偏头痛患者血液流变学改变可能为偏头痛病理改变的构成因素。

Objective To investigate the effect of acupuncture on migraine with abnormal hemorrheology.Methods 100 patients of migraine with abnormal hemorrheology were classified 5 types according to differentiation of TCM and treated by point acupuncture. Score of semiology and indexes of hemorrheology were carried on pre- and post- treatment.Results The total effective rate was 95%. Score of semiology of post-treatment (9.68±2.37) was lower than that of pre-treatment (13.76±3.65, P<0.01). Improvement of indexes of hemorrheology of post-treatment was obvious compared to that of pre-treatment (P<0.05 or P<0.01).Conclusion Acupuncture has a definite effect on migraine with abnormal hemorrheology, and could improve indexes of hemorrheology. Results indicated that changes of hemorrheology might be a factor of migraine pathological change.