高强度疏水缔合水凝胶的研究进展

Research progress of hydrophobic association hydrogels with high mechanical strength

疏水缔合水凝胶因其优异的力学性能引起了广泛的关注,被广泛应用于组织工程支架、药物载体、伤口敷料和生物传感器等智能材料中。介绍了高力学性能的疏水缔合水凝胶的不同机理。这些机理不仅包括纯疏水缔合作用,还包括了疏水缔合与乳液粒子、纳米颗粒、静电效应、金属配合物、杂化交联和双网络的协同效应。因此,疏水缔合相互作用对水凝胶在生物医学、工业、农业等领域的广泛应用具有深远的影响。

Hydrophobic association hydrogels have attracted great attention of many researchers and been widely utilized in tissue engineering stents, drug delivery carriers, wound dressings, and biosensors as intelligent materials due to their excellent mechanical strength. Here, we mainly introduced different mechanisms on hydrophobic association hydrogels with high mechanical properties. The mechanisms included not only hydrophobic association, but also synergistic effect with latex particles, nanoparticles, electrostatic effect, metal complex, hybrid crosslinking and double network. Therefore, we forecast the hydrophobic association interaction would exhibit more meaningful influence on assisting the performance of hydrogels for wide applications of biomedical, industrial, agricultural fields.