DNA改组及其应用
被引量：1
Application of DNA Shuffluing
摘要
DNA改组是一种改造基因和蛋白的有效实验进化技术。DNA改组技术在医药、疫苗、农业、生物治疗、兽药研究、营养、人类基因治疗、生物武器的研究等重要领域都具有广阔的应用开发前景。
出处
《热带医学杂志》
CAS
2002年第4期387-390,401,共5页
Journal of Tropical Medicine
参考文献14
-
1Osen W,Peiler T,Ohlschlager P,et al.A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16(HPV 16)induces E7-specific cytotoxic T cells but lacks transforming activity[J].Vaccine,2001;19(30):4276
-
2CohenJ.How DNA shuffling works[J].Science,2001,293(5528):237-237.
-
3Whalen RG,Kaiwar R,Soong NW,et al.DNA shuffling and vaccines[J].Curr Opin Mol Ther,2001;3(1):31
-
4Soong NW,Nomura L,Pekrun K,et al.Molecular breeding of viruses[J].Nat Genet,2000;25(4):436
-
5Punnonen J.Molecular breeding of allergy vaccines and antiallergic cytokines[J].Int Arch Allergy Immunol,2000;121(3):173
-
6Ryu DD,Nam DH.Recent progress in biomolecular engineering[J].Biotechnol Prog,2000;16(1):2
-
7Patten PA,Howard RJ,Stemmer WP.Application of DNA shuffling to pharmaceuticals and vaccines[J].Curr Opin Biotechnol,1997;8(6):724
-
8Moore GL,Maranas CD.Predicting Out-of-Sequence Reassembly in DNA Shuffling[J].J Theor Biol,2002;219(1):9
-
9Oh KH,Nam SH,Kim HS.Improvement of oxidative and thermostability of N-carbamyl-d-amino Acid amidohydrolase by directed evolution[J].Protein Eng,2002;15(8):689
-
10Bacher JM,Reiss BD,Ellington AD.Anticipatory evolution and DNA shuffling[J].Genome Biol,2002;3(8):1021
同被引文献41
-
1赵甫涛,贾战生,李谨革,王春雨,魏欣,白雪帆.丙型肝炎病毒C区的DNA改组[J].医学研究生学报,2006,19(3):195-198. 被引量：2
-
2Stemmer W P.Rapid evolution of a protein in vitro by DNA shuffling[J].Nature,1994,370 (6488):389-391.
-
3Stemmer W P.DNA shuffling by random fragmentation and reassembly:in vitro recombination for molecular evolution[J].Proc Natl Acad Sci,1994,91(22):10747-10751.
-
4Bacher J M,Reiss B D,Ellington A D.Anticipatory evolution and DNA shuffling[J].Genome Biol,2002,3(8):1021-1024.
-
5Crameri A,Whitehorn E A,Tate E,et al.Improved green fluorescent protein by molecular evolution using DNA shuffling[J].Nat Biotechnol,1996,14(3):315-319.
-
6Cohen J.'Breeding' antigens for new vaccines[J].Science,2001,293(5528):236-238.
-
7Luginbühl B,Kanyo Z,Jones R M,et al.Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation[J].J Mol Biol,2006,363(1):75-97.
-
8Van der Linden R H,de Geus B,Frenken G J,et al.Improved production and function of llama heavy chain antibody fragments by molecular evolution[J].J Biotechnol,2000,80(3):261-270.
-
9Crameri A,Raillard S A,Bermudez E,et al.DNA shuffling of a family of genes from diverse species accelerates directed evolution[J].Nature,1998,391(6664):288-291.
-
10Tominaga T,Hatakeyama Y.Development of innovative pediocin PA-1 by DNA shuffling among class IIa bacte-riocins[J].Appl Environ Microbiol,2007,73(16):5292-5299.
-
1韩金玉,李海静,褚巧伟,肖剑.天然药物银杏内酯研究进展[J].化工进展,2000,19(2):23-25. 被引量：15
-
2隋海霞,徐海滨,荫士安.芹菜素的生物学作用[J].国外医学（卫生学分册）,2008,35(2):103-107. 被引量：37
-
3宋国安.纤维素酶的应用开发前景[J].河南化工,1999,18(6):5-6. 被引量：6
-
4王艺军,柳兵.纤维素酶的开发应用[J].科技资讯,2007,5(7). 被引量：3
-
5卢筱华,杨冬华,汤绍辉,周旻.错配PCR和DNA改组技术提高抗肝癌单链抗体亲和力[J].中国病理生理杂志,2006,22(6):1203-1206. 被引量：2
-
6吴扬,邓婷婷,黄建安.茶树组织培养的影响因素及应用展望[J].茶叶通讯,2009,36(2):14-17. 被引量：2
-
7吕文琦.基因芯片技术在肾脏病领域中的应用展望[J].中国中西医结合肾病杂志,2002,3(5):311-312. 被引量：2
-
8金刚,蔡国平,洪水根.干细胞技术进展及其在海洋动物研究中的应用展望[J].海洋科学,2005,29(12):88-91.
-
9刘超纲.纤维素酶的工业应用展望[J].经济林研究,1996,14(1):30-31. 被引量：1
-
10李青,李晓玲.人类基因治疗[J].医学信息（云南）,1995(12):26-29.
