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经鼻面罩持续气道正压治疗重症心源性肺水肿的疗效观察

Treatment of Severe Cardiogenic Pulmonary Edema with Continuous Positive Airway Pressure by Nasal Face Mask
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摘要 目的 :为了评价经鼻面罩持续气道正压 (CPAP)对心源性肺水肿急性发作的疗效。方法 :5 1例病人随机分为两组 :治疗组 2 5例 ,吸氧浓度为 45 %加用CPAP ;对照组 2 6例 ,单用吸氧 6L/min。结果 :CPAP治疗 30min后PaO2 (P <0 .0 0 5 )明显升高 ,而呼吸频率和心率明显降低 (P <0 .0 5 ,P <0 .0 5 ) ;治疗 12h后 ,显效率为 5 2 % (13/2 5 ) ,总有效率为 88% (2 2 / 2 5 ) ,明显高于对照组 (P <0 .0 1、P <0 .0 5 )。结论 :CPAP能明显提高PaO2 ,显著改善心源性肺水肿病人的心肺功能 。 Objective:To assess the effect of continuous positive airway pressure (CPAP) by nasal face mask on the patient with cardiogenic pulmonary edema during acute episodes of the disease. Methods:51 patients with severe cardiogenic pulmonary edema were studied. Among them, 26 received oxygen alone at a flow yate of 6 liters perminutes(control group)and 25 received 45% oxygen plus CPAP by nasal face mask connecting ventilator(CPAP group).Results:PaO 2 in the CPAP was significantly increased (P&lt;0.005), whereas the respiratory rate and heart rate were significantly decreased(P&lt;0.05,P&lt;0.05) after 30 minutes. Conclusion:The CPAP could significantly improve physiologic cardiovascular and pulmonary and significantly reduce the need for intubation and mechanical ventilation in the patients with severe cardiogenic pulmonary edema.
出处 《江西医学院学报》 CAS 2002年第5期48-50,共3页 Acta Academiae Medicinae Jiangxi
关键词 疗效 心源性肺水肿 治疗 持续气道正压 病例报告 cardiogenic pulmonary edema/treatment continuous positive airway pressure case report
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