摘要
目的观察乙烯雌酚、左旋18甲基炔诺酮对SD大鼠子宫内膜NO含量的影响。方法实验分为对照组、雌激素组、孕激素组,采用Griess方法测定NO含量。结果雌激素组SD大鼠子宫内膜NO含量较对照组显著升高(P<0.01),孕激素组NO含量较对照组显著降低(P<0.01)。结论雌激素、孕激素可调节子宫内膜NO含量。
Objective To observe the effect of estrogen and progestogen on the content of nitric oxide (NO) in the endometrium of SD rats. Methods Fifteen SD rats were divided into control, estrogen and levonorgestrel groups (5 in each group), with corresponding treatment indicated by the designation of the groups. The NO contents in the endometrium were determined by Griess method. Result The NO content of estrogen group was significantly higher, while that of levonorgestrel group significantly lower, than that of the control group (P<0.01 for both comparisons). Conclusion Estrogen and levonorgestrel may regulate NO synthesis in the endometrium.
出处
《第一军医大学学报》
CSCD
北大核心
2003年第3期283-283,共1页
Journal of First Military Medical University