摘要
近年来的研究证实,激活素在肝再生、肝纤维化发生过程中起重要作用,本文对其作用的分子生物学机制以及与临床的关系进行综述。
参考文献16
-
1Woodruff TK, Krummen L, Chen SA, et al. Endocrinology,1993; 132: 725 -734
-
2Schwall RH,Robbins K,Jardieu P,et al. Hepatology, 1993;18:347-356
-
3Kogure K,Zhang YQ,Meashima A. Hepatology, 2000;31:916-921
-
4Yasuda H,Mine T,Eto Y, et al. J of Clin Invest, 1993;92:1491 - 1496
-
5De Bleser PJ,NiKi T,Xu G,et al. Hepatology, 1997;26:905-912
-
6Sugiyama M, Ichida T, Sato T, et al. Gastroenterology, 1998;114:550-558
-
7Mathews LS,Vale WW. Cell, 1992;65:973-982
-
8Heldin CH, Miyazono K,Dijke PT. Nature, 1997;390:465-471
-
9Willis SA, Zimmerman CM, Li LI, et al. Mol Endocrinol,1996; 10:367-379
-
10Chen W, Teresa K, Mayo KE. Endocrinology, 2000; 141:1263-1272
同被引文献11
-
1劳凤学,张学军,徐桂月,崔雪玲,杨煜,柳忠辉.激活素ⅡA型受体在免疫细胞上的表达[J].免疫学杂志,2004,20(5):338-342. 被引量:3
-
2姜虹,李定国,陆汉明.肝硬化患者腹水激活素A测定及其临床意义[J].中华消化杂志,2004,24(11):693-694. 被引量:1
-
3刘利宏,高大中.激活素A在动脉粥样硬化中的作用[J].国际心血管病杂志,2007,34(2):113-115. 被引量:2
-
4Yu J,Shao LE, Lemas V, et al. Importance of FSH-freleasing protein and inhibin in erythrodiffer - entiation [J ]. Nature 1987, 330(6150) : 765-767.
-
5Lau AL,Kumar TR,Nishimori K,et al. Activin beta C and beta E- genes are not essential for motase liver growth, differentiation, and regeneration[J].Mol Cell Biol, 2000,20 (18) : 6127-6137.
-
6Sugino H,Sugino K,Hashimoto O,et ah Follistatin and its role as an Aetivinbinding protein[J]. Med Invest, 1997,44(122) : 1214.
-
7Mather j P. Follistatin anda2-Maeroglobulin are soluble binding proteins for inhibin and Act ivio[J]. Biol Chem,2000,275(8) : 5485 -5492.
-
8Yamashita S,Maeshima A,Kojima l,et al. Aetivin A is a potent Activator of Renal Interstitial Fibroblasts[J]. J Am Soc Nephrol, 2004,15(1),91-101.
-
9Luisi S, Florio P,Reis FM,et al. Expression and secretion of activin A : possible - physiological and clinical implications [J ]. Eur J Endocrinol, 2001,225-236.
-
10Chen YG,Lui HM,Lin SL,et al.Regulation of cell proliferation,apoptosis,and carcinogenesis by activin[J].Exp Biol Med,2002,227(2):75-87.
-
1黄新,李定国,等.肝纤维化形成过程中ACT、FS的表达[J].胃肠病学,2001,6(C00):187-187.
-
2封英娟.激活素在大鼠试验性肝纤维化过程中的表达分析[J].中国保健营养(临床医学学刊),2009,18(6):17-19.
-
3黄新.激活素和肝纤维化[J].国外医学(消化系疾病分册),1999,19(3):158-161. 被引量:2
-
4时昭红,苏文,张介眉,刘浩,刘嵩,于皆平.银杏叶提取物对大鼠肝纤维化的治疗作用[J].中西医结合肝病杂志,2006,16(3):147-149. 被引量:5
-
5黄新,李定国.激活素、卵泡抑素与肝再生[J].国外医学(内科学分册),2000,27(3):100-102.
-
6黄新,李定国,陆汉明,魏红山,王志荣,程计林,周欣,徐芹芳.激活素A、TGFβ_1在实验性肝纤维化中的表达比较[J].中华肝脏病杂志,2001,9(6):368-368. 被引量:2
-
7黄新,李定国,李昕,王志荣,魏红山,陆汉明.激活素A在实验性肝纤维化中的表达[J].上海第二医科大学学报,2001,21(5):397-400.
-
8黄新,李定国,陆汉明,王志荣,魏红山,汪余勤,张晶,徐芹芳.激活素和卵泡抑素mRNA在肝纤维化形成过程中的作用[J].中华肝脏病杂志,2002,10(2):85-89. 被引量:13
-
9张红军,台桂香,杨清,柳忠辉.激活素在肝纤维化形成中的作用[J].临床肝胆病杂志,2007,23(3):232-234. 被引量:8
-
10王有国.高血压危害知多少[J].家庭医学(上半月),1996,0(17):21-21.