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抑肽酶在非体外循手术中应用研究进展 被引量:2

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摘要 抑肽酶可以抑制激肽释放酶原,阻断内源性凝血途径而减少凝血因子及血小板的消耗;同时可以抑制蛋白水解酶产物,抑制组织型纤溶酶原激活物(t-PA)、尿激酶型纤溶酶原激活物(u-PA)等使纤溶系统抑制而减少围术期失血及异体输血。抑肽酶可于肝移植外科、矫形外科、肿瘤外科、颅脑外科等非体外循手术中,尤其是易致纤溶系统激活的体腔手术有很好的应用前景。
出处 《国外医学(麻醉学与复苏分册)》 2003年第1期38-41,共4页 Foreign Medical Sciences(Anesthesilolgy and Resuscitation)
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  • 1Casati V, Guzzon D, Oppizzi M, et al. Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: effects on perioperative bleeding and allergenic transfusions. J Thorac Cardiovasc surg, 2000,120(3) :520~527.
  • 2Mallett SV. Cox D, Burroughs, et al. The intra-operative use of trasylol (aprotinin) in liver transplataion . transpl Int, 1991,4(4): 227-230.
  • 3Himmelreich G, Dooijewaard G, Breinl P, et al. Evolution of urokinase-type plasminogen activator(u-PA) and tissue-type plasminogen activator (t-PA) in orthotopic liver transplantation (OLT). Thromb haemost, 1993,69( 1 ): 56.
  • 4Segal Hc, Hunt BJ, Cottams, et al. Fibrinolytic activity during orthotopic liver transplantation with and without aprotinin. Transplantation. 1994,58(12): 1356-1360.
  • 5Segal HC, Hunt B J, cottams, et al. Changes in the contact system during orthotopic liver transplantation with and without aprotinin. Transplantation, 1995,59(3) :366-370.
  • 6Molenacr IQ, Legnani C, Groenland TH, et al. Aprotinin in orthotopic liver transplantation: evidence for a prohemostatic, but not a prothrombotic effect. Liver Transplant, 2001,7 (10): 896-903.
  • 7Himmelreich G, Jochum M, Bechstein WO, et al. Mediators of leukocyte activation play a role in disseminated intravascular coagulation during orthotopic liver transplantation Transplantation, 1944, 57(3):354-358.
  • 8Smith O, Hazlehurst G, Brozovic B, et al. Impact of aprotinin on blood tranafusion requirements in liver transplantatian Transfus Med,1993,3(2) :97-102.
  • 9Scudamore CH, Randall TE, Jewesson PJ, et al. Aprotinin reduces the need for blood products during liver transplantation. Am J Surg;1995,169(5) :546-549.
  • 10Monedero P, Paramo JA, Garrascosa F, et al. Reduction of the need for blood derivatives in liver transplantation using aprotinin. Rev Esp Anestesiol Reanim, 1995,42(3): 82-86.

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  • 1Sodha NR, Boodhwani M, Bianchi C, et al. Aprotinin in cardiac surgery. Expert Rev Cardiovasc Ther, 2006, 4:151 - 160.
  • 2Niimi KS. Aprotinin dosing: how much is enough? J Extra Corper Technol, 2004, 36:384 - 390.
  • 3Vetsuj S, Yamamura M, Takai S, et al. Effect of aprotinin on metastasis of lewis Lung tumor in mice. Surg Today, 1992, 22:439 - 442.
  • 4Palmer JD, Francis JL, Pickard JD, et al. The efficacy and safety of aprotinin for hemostasis during intracranial surgery. J Neurosurg, 2003, 98:1208 - 1216.
  • 5Vaporciyan AA, Putnam JB, Smythe WR. The potential role of aprotinin in the perioperative management of malignant tumors. J Am Coll Surg, 2004, 198:266 - 278.
  • 6李滨滨,姜丽华,王国年,孙学超.围术期应用抑肽酶减少脑肿瘤手术出血及脑水肿的临床研究(附60例分析)[J].哈尔滨医科大学学报,2001,35(2):131-132. 被引量:11

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