细胞学图像中细胞核染色质特征提取方法研究

Cytology Images Chromatin Feature Extraction Method

针对宫颈细胞学涂片图像分析中需要描述细胞核染色质颗粒大小和染色质分布均匀度的需求,提出了一种基于数学形态学的颗粒分析方法来描述细胞核的染色质颗粒大小,使用以细胞核质心为起点的各条辐射线上的颜色深度的方差来描述染色质分布的均匀度。文中具体描述了两种染质特征提取的算法,并用实验证明了用提取的染色质特征描述细胞核图像的染色质特征的有效性和可行性。

This paper focused on the requirements of describing particle size and distribution uniformity of nuclear chromatin in image analysis of cervical cytology,proposed a mathematical morphology-based particle analysis method to describe particle size of nuclear chromatin.In this method,the distribution uniformity of chromatin is described using the variance of color depth of each radiation line whose starting point is the centroid of nuclei.It described two specific chromatin feature extraction algorithm.The experiments prove that the proposed chromatin described features can be more effective nuclear chromatin image characteristics.