摘要
有些癫痫患者存在细胞和体液免疫功能的异常。细胞免疫功能的异常包括T淋巴细胞亚群、细胞因子及NK细胞活性紊乱等异常。深入研究癫痫患者的细胞免疫功能,尤其是T淋巴细胞亚群与癫痫的关系,对于揭示癫痫发病机理有极其重要的意义。
出处
《国外医学（神经病学．神经外科学分册）》
2003年第1期45-48,共4页
Foreign Medical Sciences（Section On Neurology & Neurosurgery）
参考文献16
-
1[1]Eog-Olofsson O,Prchal JF,Andermann F,et al.Abnormolities of T -lymphocyte subsets in epileptic patients.Acta Neurol Scand,1985,72(2):140-144.
-
2[2]Marcoli M,Gatti G,Ippoliti G,et al.Effect of chronic anticonvulsant monotherapy on lymphocyte subpopulations in adult epileptic patients.Hum l,1985,4:147.
-
3[3]Bostantjopoulou S,Hatzizisi O,Arggropoulou O,et al.Immunological parameters in patients with epilepsy.Funct Neurol,1994,9(1):11-15.
-
4[4]Vlajkovic S,Jankovic BD.xperimental epilepsy:electrically and chemically induced convulsions modulate experimental allergic encephalomyelitis and other immune in flammatory reactions in the rat.Intern J Neurosci,1990,54(1-2):165-172.
-
5[5]Pacifici R,Zuccaro P,Iannetti P,et al.Immunologic aspects of Vigabatrin treatment in epileptic children.Epilepisia,1995,36(4):423-426.
-
6[6]Sheng JG,Boop FA,Mark RE,et al.Increase ad neuronal beta-amyloid precursor protein expression in human temporal lobe epilepsy:association with interleukin-1alpha immunoreactivity.J Neurochem,1994,63(5):1872-1879.
-
7[7]Vezzani A,Conti M,De Luigi A,et al.Interleukin-beta immunoreactivity and microglia are enhanced in rat hippocampus by focal kainate application:functional evidence for enhancement of electrographic seizures.J Neurosci,1999,19(12):5054-5065.
-
8[8]Vezzani A,Moneta D,Conti M,et al.powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice.Proc Natl Acad Sci USA,2000,97(21):11534-11539.
-
9[9]Liu ZS,Wang QW,Wang FL,et al.Serum cytokine levels are altered in patients with West syndrome.Brain Dev,2001,23(7):548-551.
-
10[10]Peltola J,Palmio J,Korhonen L,et al.Interleukin-6 and interleukin-1receptor antagonist in cerebrospinal fluid from patients with recent tonic-clonic seizures.Epilepsy Res,2000,41(3):205-211.
同被引文献7
-
1Bostantjopoutou S,Kyriazis G,Hatzixisi O,et al,Cytokines and serum immunoglobulins in epileptic patients.Epilepsia,1994,16,172
-
2Arditi M,Manogue KR,Caplan M,et al.Cerebrospinal fluid cathetin tumor necrosis factor-alpha and platelet-activating factor concentrations and severity of bacterial menigitis in children .J Infect Dis, 1990,162(1):139
-
3Merrill JE, Jonakait GK .Interactions of the nervous and immune systems in development.normal brain homeostasis and disease.FASEB J,1995,9(8):611
-
4Chao CC,Hus.TNF-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures, Dev Neurosci,1994,16(3-4):172
-
5Beattie EC,Stellwagen D,Morishita W,et al. Control of synaptic strength by glial TNFα. Science,2002,295(5 563):2 282
-
6梁英武,单巍松,张国荣,王朝晖,吴希如.IL-2对神经元NMDAR_1 mRNA表达和细胞内钙浓度的影响[J].中华微生物学和免疫学杂志,1997,17(4):295-297. 被引量：18
-
7王献,陈品,屈宝华,齐进兴.高血压性脑出血并发肺部感染患者T淋巴细胞亚群和TNFα的变化[J].郑州大学学报（医学版）,2004,39(1):100-102. 被引量：3
-
1李罗清,孙圣刚,徐金枝,杨明山.糖皮质激素对重症肌无力患者细胞和体液免疫功能影响的研究[J].临床内科杂志,2004,21(5):334-336. 被引量：7
-
2张敏,王晓川,王艺.抗癫药物对免疫功能的影响[J].实用儿科临床杂志,2009,24(9):703-705. 被引量：1
-
3韦启后,覃志坚,覃淑云.急性脑缺血性大鼠细胞免疫功能初探[J].广西医科大学学报,2002,19(2):250-250. 被引量：2
-
4黄煜敏,林嘉友,许贤豪,郭采青,谭铭勋,邬瑞华.重症肌无力患者自然杀伤细胞的研究[J].中国神经免疫学和神经病学杂志,1994,1(1):32-35. 被引量：1
-
5刘小林,马筠,谌必胜,邝培桂,张铭莉,毕爱华,黄灿辉.氯丙嗪对精神分裂症患者外周血NK细胞活性的影响[J].临床精神医学杂志,1998,8(3):132-132.
-
6宁泽晖,刘积平.针灸对缓解期脑梗死患者淋巴细胞亚群的影响[J].四川中医,2008,26(2):110-111. 被引量：3
-
7李天富.癫痫与免疫[J].国外医学（神经病学．神经外科学分册）,1998,25(1):24-27. 被引量：3
-
8时学英.逍遥散治疗肝郁脾虚型慢性疲劳综合征的疗效及其对患者免疫功能的影响[J].浙江中医杂志,2007,42(7):394-395. 被引量：20
-
9伍志臻,陈福国,陈秀琴.五项细胞免疫指标与抑郁性神经症的相关性研究[J].上海医学检验杂志,1999,14(5):280-281. 被引量：13
-
10吴梅,蔡方成.不同类型格林-巴利综合征急性期免疫学改变[J].四川医学,2005,26(9):1018-1020. 被引量：1
