茵陈治疗ABO母儿血型不合206例疗效观察

Treatment of ABO Blood Group Incompatibility in Pregnant Women and Infant by Herba Artemisiae Scopariae: A Clinical Observation of 206 Cases

目的:观察大剂量茵陈治疗孕妇母儿血型不合的临床疗效。方法:将388例母儿血型不合孕妇随机分为2组,A组206例,给予单味茵陈治疗;B组182例,给予传统的复方茵陈汤治疗。每2～4周复查血清免疫性抗体效价,并比较2组有效率的差异。结果:有效率A组(83.5％)高于B组(78.0％),但差异无显著性意义(P>0.05)。结论:大剂量茵陈治疗孕妇母儿血型不合的疗效与传统复方茵陈汤相仿,但具有简单、易行,无毒副作用的优点,对妊娠期用药安全有重要的意义。

Objective: To observe the elinical effect of large dosage of Herba Artemisiae Scopariae(HAS) for blood group incompatibility (BGI) in pregnant women. Methods: 388 cases of BGI in pregnant women were allocated to two groups randomly. Croup A (206 cases) were treated by HAS alone; Group H(182 cases) were treated by conventional prescription. The tiler ot seroimmunity antibody was examined every 2-4 weeks and the difference was compared between two groups. Results: The effective rate was 83. 5% in group A and 78. 0% in group B( P > 0. 05) . Conclusion: The curative effect of large dosage of HAS is similar to conventional prescription, but the former is more simple and convenient and no toxic and side effect are observed, and is safe for pregnant period.