42例脑梗死后痴呆临床分析

A clinical study of 42 cases with dementia after cerebral infarction

目的 分析 4 2例脑梗死后痴呆的发病情况 ,探讨产生痴呆的影响因素。方法 所有病人在入院时及发病后 3个月均进行临床和智能评估 ,入院时均行头颅 CT/ MRI检查 ,痴呆的诊断参照简明精神状态量表 (MMSE)和美国精神病学会编《精神病诊断和治疗手册》第 4版 (DSM- IV)。结果 3个月后随访有 4 2例患者 (15 .8% )出现脑梗死后痴呆 ,痴呆的发生与高龄 ,文化程度低 ,高血压 ,糖尿病 ,脑梗死的部位、侧向、数目等有关。结论 脑梗死后痴呆比较常见 ,患者自身素质 (如年龄、文化程度 ) ,导致动脉粥样硬化的血管因素 (如高血压、糖尿病 ) ,以及脑梗死病灶的相关因素 (如部位、侧向、数目 )

Objective The 42 patients with dementia after cerebral in infarction were studied.Methods A protocol was applied at admission and 3 months after stroke;this protocol included clinical,cognitive assessments,and head CT or MRI exams.The following diagnostic criteria were used:the Diagnostic and Statistical Manual of Mental Disorders(DSM IV),and the Mini Mental State Examination(MMSE).Results 42 cases(15 8%)demonstrated dementia at 3 month follow up.Dementia was related to older?low lever of education?hypertension?diabetes and location or numbers of cerebral infarction.Conclusion Dementia is frequent after cerebral infarction.Age,lever of education,hypertension,diabetes and location or numbers of cerebral infarction may play an important role.