连续性肾脏替代与间歇性血液透析治疗多器官功能障碍综合征的疗效比较(附18例分析)

The match of continuous renal replacement therapy and intermitten hemodialysis on multiple organ dysfunction syndrome with acute rend failure

目的 比较连续性肾脏替代治疗 (CRRT)与间歇性血液透析 (IHD)治疗伴有急性肾功能衰竭(ARF)的多器官功能障碍综合征 (MODS)患者的疗效。方法 18例伴 ARF的 MODS患者 ,8例接受 CRRT,10例接受隔日 1次的 IHD,观察每日液体摄入量 ,每日晨检查血肌酐、尿素氮、血碳酸氢根浓度、血 p H值。结果 CRRT组和 IHD组每日摄入量有显著性差异 (P<0 .0 5 )。 CRRT组较少出现透析相关低血压及容量依赖性心功能衰竭 ,且肌酐、尿素氮、碳酸氢根、 p H值较稳定 (P<0 .0 5 )。结论 CRRT控制伴 ARF的 MODS患者液体酸碱平衡、氮质血症优于 IHD。

Obective To explore the effect of continuous renal replacement therapy and intermitten hemodialysis on multiple organsdysfunction syndrome with acute rend failure.Methods 18 Patients with multiple oragan dysfunction syndrome and acute renal failure were chosen.They were divided into two groups with different dialyzer:CRRT and IHD.The blood flow kinetics,pulse and serum biochemistry were monitored.Results The difference between CRRT groups and IHD groups daily intake was significant(p<0.05).There was less possibility of hemodialysis related hypotension and volumn dependent heart failure for CRRT group,and creatinine,urine nitrogen,HCO 3,pH value for CRRT group were move stable(P<0.05).Conclusion The effect of CRRT has more advantage over that of IHD for those patients sufferecd from MODS with ARF.